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Title: The mid-term outcome of geometric endoventricular repair for the patients with ischemic left ventricular dysfunction.
Austin Authors: Hata, Mitsumasa;Raman, Jai S ;Storer, Meg ;Matalanis, George ;Rosalion, Alexander;Buxton, Brian F ;Hare, David L 
Affiliation: Department of Cardiac Surgery, Austin & Repatriation Medical Centre, University of Melbourne, Melbourne, Australia
Issue Date: 1-Aug-2003
Publication information: Annals of Thoracic and Cardiovascular Surgery : Official Journal of the Association of Thoracic and Cardiovascular Surgeons of Asia; 9(4): 241-4
Abstract: Recent studies have suggested that increased left ventricular (LV) size is a risk factor for perioperative mortality in patients with low ejection fraction (EF) undergoing coronary artery bypass surgery (CABG). We previously presented a new method of LV reconstruction, called geometric endoventricular repair (GER) as representing a physiologically effective repair. The aim of this study is to assess whether GER confers benefits compared to patients undergoing CABG alone.Between July 1996 and July 2001, 110 patients with a low EF of less than 35% documented by radionuclide ventriculogram (RNVG) underwent CABG in Austin Hospital, Australia, and were divided into two groups. Group I consisted of 52 patients undergoing isolated CABG. Group II comprised 58 patients undergoing CABG and GER. We compared the two groups in terms of EF, NYHA class, incidence of recurrent heart failure, and mortality.Preoperative EF was 27.7+/-6.1% in group I and 27.4+/-5.7% in group II, respectively (NS), with significant improvement in both groups (33.8+/-13.0% in group I, 35.1+/-13.3% in group II). NYHA class was also significantly improved postoperatively (from 3.3 to 1.8 in group I, and 3.6 to 1.7 in group II). There were 15 patients (28.8%) hospitalized for heart failure in group I, postoperatively, compared to seven patients (10.9%) in group II (p=0.026). Cardiac event-free survival rate at 28 months (mean follow-up) was also significantly higher in group II (88.9% in group II vs. 70.6% in group I, p=0.05). The actuarial survival rate at 31 months (mean follow-up) was 88.2% in group I and 95.3% in group II, respectively (NS).LV reconstruction along with CABG for ischemic ventricular dysfunction may provide symptomatic and cardiac event free survival benefits, compared to CABG alone.
Gov't Doc #: 13129422
ORCID: 0000-0001-9554-6556
PubMed URL: 13129422
Type: Journal Article
Subjects: Aged
Coronary Artery Bypass.adverse effects.methods
Follow-Up Studies
Middle Aged
Survival Rate
Time Factors
Treatment Outcome
Ventricular Dysfunction,
Appears in Collections:Journal articles

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