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Title: Hippocampal Volume and Amyloid PET Status Three Years After Ischemic Stroke: A Pilot Study.
Austin Authors: Brodtmann, Amy ;Khlif, Mohamed Salah;Bird, Laura J;Cumming, Toby B ;Werden, Emilio 
Affiliation: Eastern Cognitive Disorders Clinic, Box Hill Hospital, Monash University, Box Hill, VIC, Australia
Department of Neurology, Royal Melbourne Hospital, Parkville, VIC, Australia
The Florey Institute of Neuroscience and Mental Health, University of Melbourne, Melbourne VIC, Australia
Issue Date: 2021 2021-02-04
Publication information: Journal of Alzheimer's disease : JAD 2021; 80(2): 527-532
Abstract: Hippocampal atrophy is seen in many neurodegenerative disorders and may be a cardinal feature of vascular neurodegeneration. We examined hippocampal volume (HV) in a group of ischemic stroke survivors with amyloid 18F-NAV4694 PET imaging three years after stroke. We compared HV between the amyloid-positive (n = 4) and amyloid-negative (n = 29) groups, and associations with co-morbidities using Charlson Comorbidity Indices and multi-way ANOVA. Amyloid status was not associated with verbal or visual delayed free recall memory indices or cognitive impairment. We found no association between amyloid status and HV in this group of ischemic stroke survivors.
DOI: 10.3233/JAD-201525
PubMed URL: 33554919
Type: Journal Article
Subjects: 18F-NAV4694
Amyloid imaging
hippocampal volume
ischemic Stroke
Appears in Collections:Journal articles

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