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Title: Long-term recovery following critical illness in an Australian cohort.
Austin Authors: Haines, Kimberley J ;Berney, Susan C ;Warrillow, Stephen J ;Denehy, Linda
Affiliation: Physiotherapy Department, Western Health, St. Albans, Victoria, Australia
Department of Physiotherapy, Melbourne School of Health Sciences, The University of Melbourne, Parkville, Victoria, Australia
Department of Physiotherapy, Austin Health, Heidelberg, Victoria, Australia
Department of Intensive Care, Austin Health, Heidelberg, Victoria, Australia
Issue Date: 2018
Date: 2018-02-05
Publication information: Journal of intensive care 2018; 6: 8
Abstract: Almost all data on 5-year outcomes for critical care survivors come from North America and Europe. The aim of this study was to investigate long-term mortality, physical function, psychological outcomes and health-related quality of life in a mixed intensive care unit cohort in Australia. This longitudinal study evaluated 4- to 5-year outcomes. Physical function (six-minute walk test) and health-related quality of life (Short Form 36 Version 2) were compared to 1-year outcomes and population norms. New psychological data (Center for Epidemiological Studies-Depression, Impact of Events Scale) was collected at follow-up. Of the 150 participants, 66 (44%) patients were deceased by follow-up. Fifty-six survivors were included with a mean (SD) age of 64 (14.2). Survivors' mean (SD) six-minute walk distance increased between 1 and 4 to 5 years (465.8 m (148.9) vs. 507.5 m (118.2)) (mean difference = - 24.5 m, CI - 58.3, 9.2, p = 0.15). Depressive symptoms were low: median (IQR) score of 7.0 (1.0-15.0). The mean level of post-traumatic stress symptoms was low-median (IQR) score of 1.0 (0-11.0)-with only 9 (16%) above the threshold for potentially disordered symptoms. Short-Form 36 Physical and Mental Component Scores did not change between 1 and 4 to 5 years (46.4 (7.9) vs. 46.7 (8.1) and 48.8 (13) vs. 48.8 (11.1)) and were within a standard deviation of normal. Outcomes of critical illness are not uniform across nations. Mortality was increased in this cohort; however, survivors achieved a high level of recovery for physical function and health-related quality of life with low psychological morbidity at follow-up. The trial was registered with the Australian New Zealand Clinical Trials Registry ACTRN12605000776606.
DOI: 10.1186/s40560-018-0276-x
ORCID: 0000-0002-2882-1594
Journal: Journal of intensive care
PubMed URL: 29445502
ISSN: 2052-0492
Type: Journal Article
Subjects: Critical illness
Long-term outcomes
Appears in Collections:Journal articles

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