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Title: Mitral regurgitation: comparison between edge-to-edge repair and valve replacement.
Austin Authors: Raman, Jai S ;Shah, Pallav;Seevanayagam, Siven ;Cheung, John;Buxton, Brian F 
Affiliation: Department of Cardiac Surgery, Austin Hospital, Heidelberg, Melbourne, Victoria 3084, Australia
Issue Date: 1-Jun-2003
Publication information: Asian Cardiovascular & Thoracic Annals; 11(2): 131-4
Abstract: Mitral regurgitation due to bileaflet prolapse and ischemic causes can be difficult to repair. Midterm experience of the Alfieri edge-to-edge repair as an alternative to valve replacement is reported. Twenty-six patients with severe mitral regurgitation underwent the Alfieri repair between January 1998 and December 2000 (group 1); 15 cases were due to bileaflet prolapse and 7 were of ischemic origin. During the same period, valve replacement was performed in 36 patients (group 2), 20 of whom had similar indications. Follow-up was complete to a mean of 15 months (range, 1-28 months). There was no early death in either group. During follow-up, there was no reoperation in group 1, while 2 patients in group 2 required reoperations due to prosthetic valve endocarditis. There were 4 major thromboembolic or bleeding events in group 2, and none in group 1. All patients in group 1 had trivial to mild mitral regurgitation on follow-up echocardiography. The mean mitral valve gradient was significantly higher in group 2 compared to group 1 (7.2 versus 3.2 mm Hg, p = 0.001). The edge-to-edge repair is associated with good early and midterm results. Long-term follow-up is required to evaluate the durability of this technique.
Gov't Doc #: 12878560
Type: Journal Article
Subjects: Aged
Cardiac Surgical Procedures.methods
Heart Valve Prosthesis
Middle Aged
Mitral Valve
Postoperative Complications
Treatment Outcome
Appears in Collections:Journal articles

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