Please use this identifier to cite or link to this item: https://ahro.austin.org.au/austinjspui/handle/1/33145
Title: The effect of gender-affirming hormone therapy on hair growth: A systematic review of the literature.
Austin Authors: Tang, Gia Toan;Zwickl, Sav;Sinclair, Rodney;Zajac, Jeffrey D ;Cheung, Ada S 
Affiliation: Endocrinology
Sinclair Dermatology, East Melbourne, Victoria 3002, Australia.
Medicine (University of Melbourne)
Issue Date: 19-Sep-2023
Date: 2023
Publication information: Clinical and Experimental Dermatology 2023-09-19; 48(10)
Abstract: Gender affirming hormone therapy (GAHT) leads to changes in body composition, secondary sex characteristics and in the distribution and pattern of hair growth. Transgender individuals undergoing GAHT may experience altered hair growth patterns that may be affirming and desirable, or undesirable with subsequent impacts on quality of life. Given increasing numbers of transgender individuals commencing GAHT worldwide and clinical relevance of the impact of GAHT on hair growth, we systematically reviewed the existing literature on the impact of GAHT on hair changes and androgenic alopecia (AGA). The majority of studies used grading schemes or subjective measures of hair changes based on patient or investigators' examination. Very few studies used objective quantitative measures of hair parameters but demonstrated statistically significant changes in hair growth length, diameter and density. Feminizing GAHT with estradiol and/or antiandrogens in trans women may reduce facial and body hair growth, and can improve AGA. Masculinizing GAHT with testosterone in trans men may increase facial and body hair growth as well as induce or accelerate AGA. The impact of GAHT on hair growth may not align with a transgender person's hair growth goals and specific treatment for AGA and/or hirsutism may be sought. Further research on how GAHT affects hair growth is required.
URI: https://ahro.austin.org.au/austinjspui/handle/1/33145
DOI: 10.1093/ced/llad203
ORCID: 0000-0001-6826-131X
0000-0003-2959-5928
0000-0001-6751-1428
0000-0003-3933-5708
0000-0001-5257-5525
Journal: Clinical and Experimental Dermatology
PubMed URL: 37311161
ISSN: 1365-2230
Type: Journal Article
Appears in Collections:Journal articles

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