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Title: | Outcomes in grade 3B follicular lymphoma: an international study led by the Australasian Lymphoma Alliance. | Austin Authors: | Barraclough, Allison ;England, James T;Villa, Diego;Wight, Joel C ;Hapgood, Greg;Conn, Jason;Doo, Nicole Wong;Li, Eric Wenlong;Gilbertson, Michael;Shaw, Briony;Bishton, Mark J;Saeed, Malik;Ratnasingam, Sumita;Abeyakoon, Chathuri;Chong, Geoff;Wai, Shin Hnin;Ku, Matthew;Lee, Hui-Peng;Fleming, Kathryn;Tam, Constantine;Douglas, Genevieve ;Cheah, Chan Y;Ng, Zi Yun;Rolfe, Tukten;Mills, Anthony K;Hamad, Nada;Cashman, Helen;Gleeson, Mary;Narayana, Manjunath;Hawkes, Eliza A | Affiliation: | Fiona Stanley Hospital, Department of Haematology, Perth, Australia; University of Melbourne, Melbourne. University of British Columbia and BC Cancer Centre for Lymphoid Cancer, Vancouver, Canada; Princess Margaret Cancer Centre, Toronto. University of British Columbia and BC Cancer Centre for Lymphoid Cancer, Vancouver. University of Melbourne, Melbourne, Australia; Townsville University Hospital, Department of Haematology, Townsville. Princess Alexandra Hospital, Department of Haematology, Brisbane. Concord Clinical School, University of Sydney, Sydney. Monash Health, Department of Haematology, Melbourne, Australia; School of Clinical Sciences, Monash University, Melbourne. Monash Health, Department of Haematology, Melbourne. Nottingham City Hospital, Department of Haematology, Nottingham. University Hospital Geelong, Department of Haematology, Geelong. University of Melbourne, Melbourne, Australia; Ballarat Regional Integrated Cancer Centre, Ballarat Health Services, Melbourne, Australia; Department of Medical Oncology and Haematology, Olivia Newton-John Cancer Research and Wellness Centre, Austin Health, Melbourne. University of Melbourne, Melbourne, Australia; St Vincent's Hospital Melbourne, Department of Haematology, Melbourne. Flinders Medical Centre, Department of Haematology, Adelaide. Flinders Medical Centre, Department of Haematology, Adelaide. University of Melbourne, Melbourne, Australia; Peter MacCallum Cancer Centre and Royal Melbourne Hospital, Department of Haematology, Melbourne. Department of Medical Oncology and Haematology, Olivia Newton-John Cancer Research and Wellness Centre, Austin Health, Melbourne. Sir Charles Gairdner Hospital, Department of Haematology, Perth, Australia; University of Western Australia, Medical School, Perth. Sir Charles Gairdner Hospital, Department of Haematology, Perth. Greenslopes Private Hospital, Brisbane. St Vincent's Hospital Sydney, Department of Haematology, Sydney, Australia; School of Clinical Medicine, University of New South Wales, Sydney, Australia; School of Medicine, University of Notre Dame, Sydney. St Vincent's Hospital Sydney, Department of Haematology, Sydney. Guy's and St. Thomas' NHS Foundation Trust, Department of Haematology, London. Sunshine Coast University Hospital, Department of Haematology, Birtinya. Medical Oncology Olivia Newton-John Cancer Research Institute Clinical Haematology |
Issue Date: | 1-Sep-2023 | Date: | 2023 | Publication information: | Haematologica 2023; 108(9) | Abstract: | Grade (G) 3B follicular lymphoma (FL) is a rare FL subtype which exists on a histological continuum between 'low-grade' (Grade 1, 2 and 3A FL) and diffuse large B-cell lymphoma (DLBCL) appearing to share features with each. Clinical characteristics and outcomes are poorly understood due to lack of adequate representation in prospective trials and large-scale analyses. We analyzed 157 G3BFL cases from 18 international centers, and two comparator groups; G3AFL (n=302) and DLBCL (n=548). Composite histology with DLBCL or low-grade FL occurred in approximately half of G3BFL cases. With median 5 years follow-up, G3BFL overall (OS; P. | URI: | https://ahro.austin.org.au/austinjspui/handle/1/32212 | DOI: | 10.3324/haematol.2022.281375 | ORCID: | Journal: | Haematologica | PubMed URL: | 36815381 | ISSN: | 1592-8721 | Type: | Journal Article | Subjects: | follicular lymphoma |
Appears in Collections: | Journal articles |
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