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https://ahro.austin.org.au/austinjspui/handle/1/32058| Title: | Tenecteplase Treatment and Thrombus Characteristics Associated With Early Reperfusion: An EXTEND-IA TNK Trials Analysis. | Austin Authors: | Yogendrakumar, Vignan;Churilov, Leonid ;Guha, Prodipta;Beharry, James;Mitchell, Peter J;Kleinig, Timothy J;Yassi, Nawaf;Thijs, Vincent N ;Wu, Teddy Y;Brown, Helen;Dewey, Helen M;Wijeratne, Tissa;Yan, Bernard;Sharma, Gagan;Desmond, Patricia M;Parsons, Mark W;Donnan, Geoffrey A ;Davis, Stephen M;Campbell, Bruce C V | Affiliation: | Department of Neurology, Royal Melbourne Hospital, University of Melbourne, Parkville, Australia. Department of Radiology, Royal Melbourne Hospital, Parkville, Australia (P.J.M., B.Y., P.M.D.). Department of Neurology, Royal Adelaide Hospital, Australia (T.J.K.). General Medicine Department of Neurology, Christchurch Hospital, New Zealand (T.Y.W.). Department of Neurology, Princess Alexandra Hospital, Brisbane, Queensland, Australia (H.B.). Department of Neurosciences, Eastern Health and Eastern Health Clinical School, Clayton, Victoria, Australia (H.M.D.). Melbourne Medical School, Department of Medicine and Neurology, University of Melbourne and Western Health, St Albans, Australia (T.W.). |
Issue Date: | 2-Feb-2023 | Date: | 2023 | Publication information: | Stroke 2023; 54(3) | Abstract: | Intracranial occlusion site, contrast permeability, and clot burden are thrombus characteristics that influence alteplase-associated reperfusion. In this study, we assessed the reperfusion efficacy of tenecteplase and alteplase in subgroups based on these characteristics in a pooled analysis of the EXTEND-IA TNK trial (Tenecteplase Versus Alteplase Before Endovascular Therapy for Ischemic Stroke). | URI: | https://ahro.austin.org.au/austinjspui/handle/1/32058 | DOI: | 10.1161/STROKEAHA.122.041061 | ORCID: | 0000-0001-8814-6853 0000-0002-9807-6606 0000-0002-4932-954X 0000-0002-8337-7529 0000-0003-4430-3276 0000-0002-0685-0060 0000-0002-6614-8417 0000-0003-1845-1769 0000-0001-9142-2708 0000-0001-9484-2070 0000-0002-1701-7111 0000-0001-8802-9606 0000-0002-4803-6323 0000-0001-8874-2487 0000-0001-6324-3403 0000-0003-0962-2300 0000-0003-3632-9433 |
Journal: | Stroke | PubMed URL: | 36727510 | ISSN: | 1524-4628 | Type: | Journal Article | Subjects: | carotid artery reperfusion tenecteplase thrombus tomography |
| Appears in Collections: | Journal articles |
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