Austin Health

Title
Enhancing generalizability of stroke clinical trial results: Illustrations from upper-limb motor recovery trials.
Publication Date
2023-06
Author(s)
Dalton, Emily J
Lannin, Natasha A
Campbell, Bruce Cv
Churilov, Leonid
Hayward, Kathryn S
Subject
Stroke
clinical trial
rehabilitation
stroke rehabilitation
upper extremity
validity
Type of document
Journal Article
OrcId
0000-0003-3920-8530
0000-0002-2066-8345
0000-0003-3632-9433
#PLACEHOLDER_PARENT_METADATA_VALUE#
0000-0001-5240-3264
DOI
10.1177/17474930221135730
Abstract
Broadening eligibility criteria has been a focus to increase the generalizability of trial findings. Using upper-limb motor trials conducted early post-stroke as the illustrative domain, we sought to (1) investigate whether the published aim and conclusion statements adequately reflect the generalizability of findings and (2) explore internal validity and feasibility as constraints to achieving generalizability.
Link
Citation
International Journal of Stroke 2023; 18(5)
Jornal Title
International Journal of Stroke
ISSN
1747-4949

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