Please use this identifier to cite or link to this item: https://ahro.austin.org.au/austinjspui/handle/1/31018
Title: The Association Between Sarcopenia and Functional Improvement in Older and Younger Patients Who Completed Inpatient Rehabilitation: A Prospective Cohort Study.
Austin Authors: Churilov, Irina;Churilov, Leonid ;Brock, Kim;Murphy, David;MacIsaac, Richard J;Ekinci, Elif I 
Affiliation: Endocrinology
Department of Physiotherapy, St Vincent's Hospital Melbourne, Fitzroy, VIC, Australia
Department of Endocrinology and Diabetes, St Vincent's Hospital Melbourne, Fitzroy, VIC, Australia
Department of Rehabilitation, St Vincent's Hospital Melbourne, Fitzroy, VIC, Australia
Medicine (University of Melbourne)
Melbourne Brain Centre at Royal Melbourne Hospital, Melbourne Medical School, The University of Melbourne, Parkville, VIC, Australia
Issue Date: 2021
Date: 2021
Publication information: Frontiers in Rehabilitation Sciences 2021; 2: 692896
Abstract: Objective: To investigate the association between sarcopenia and functional improvement in patients older and younger than 65 years upon completion of an inpatient rehabilitation program. Design: Prospective cohort study. Participants: Adult consecutive patients who completed the inpatient rehabilitation program at a metropolitan tertiary referral hospital general inpatient rehabilitation unit. Methods: Sarcopenia status was determined using the European Working Group on Sarcopenia in Older People 2 algorithm, using muscle mass measured by BioImpedance Analysis and grip strength. Progress in rehabilitation was measured using change in the Functional Independence Measure and Goal Attainment Scaling score. To investigate the age group by sarcopenia status interaction we used quantile regression models with bootstrapped standard error estimation for functional improvement and linear regression model with robust standard error estimation for GAS score. Results: 257 participants [128 (50%) male, median age 63 years (IQR: 52-72)], 33(13%) with sarcopenia, completed inpatient rehabilitation [median length of stay 16 days (IQR: 11-27.5)]. Participants' median Functional Independence Measure change was 24 (IQR 15-33.5) and mean total Goal Attainment Scaling score was 57.6 (SD 10.2). Adjusting for admission Functional Independence Measure score, the median difference in Functional Independence Measure change between participants with and without sarcopenia was: -4.3 (95% CI: -10.6, 1.9); p = 0.17 in participants 65 years and younger, and 4.6 (95% CI: 1.0, 8.2); p = 0.01 in participants older than 65; age-by-sarcopenia interaction p = 0.02. Conclusions: Unlike younger people, older people with sarcopenia have greater functional improvement in inpatient rehabilitation than those without sarcopenia.
URI: https://ahro.austin.org.au/austinjspui/handle/1/31018
DOI: 10.3389/fresc.2021.692896
Journal: Frontiers in Rehabilitation Sciences
PubMed URL: 36188786
Type: Journal Article
Subjects: functional improvement
inpatient rehabilitation
muscle
rehabilitation
sarcopenia
Appears in Collections:Journal articles

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