Comparing treatment outcomes of various intracranial bifurcation aneurysms locations using the Woven EndoBridge (WEB) device.

2022-04-28

Adeeb, Nimer

Dibas, Mahmoud

Diestro, Jose Danilo Bengzon

Phan, Kevin

Cuellar-Saenz, Hugo H

Sweid, Ahmad

Lay, Sovann V

Guenego, Adrien

Aslan, Assala

Renieri, Leonardo

Sundararajan, Sri Hari

Saliou, Guillaume

Möhlenbruch, Markus

Regenhardt, Robert W

Vranic, Justin E

Lylyk, Ivan

Foreman, Paul M

Vachhani, Jay A

Župančić, Vedran

Hafeez, Muhammad U

Rutledge, Caleb

Waqas, Muhammad

Tutino, Vincent M

Rabinov, James D

Ren, Yifan

Schirmer, Clemens M

Piano, Mariangela

Kuhn, Anna L

Michelozzi, Caterina

Elens, Stephanie

Starke, Robert M

Hassan, Ameer

Salehani, Arsalaan

Brehm, Alex

MohammedAli, MajdEddin

Jones, Jesse

Psychogios, Marios

Spears, Julian

Lubicz, Boris

Panni, Pietro

Puri, Ajit S

Pero, Guglielmo

Griessenauer, Christoph J

Asadi, Hamed

Siddiqui, Adnan

Ducruet, Andrew

Albuquerque, Felipe C

Du, Rose

Kan, Peter

Kalousek, Vladimir

Lylyk, Pedro

Stapleton, Christopher J

Boddu, Srikanth

Knopman, Jared

Aziz-Sultan, Mohammad A

Limbucci, Nicola

Jabbour, Pascal

Cognard, Christophe

Patel, Aman B

Dmytriw, Adam A

Aneurysm

Journal Article

http://orcid.org/0000-0001-8450-2021

http://orcid.org/0000-0002-8348-4535

http://orcid.org/0000-0002-2652-2451

http://orcid.org/0000-0003-4105-0664

http://orcid.org/0000-0001-7281-1652

http://orcid.org/0000-0003-3832-7976

http://orcid.org/0000-0002-6000-6709

http://orcid.org/0000-0002-6048-4225

http://orcid.org/0000-0003-4500-7954

http://orcid.org/0000-0002-1331-2551

http://orcid.org/0000-0001-6518-6828

http://orcid.org/0000-0001-6339-448X

http://orcid.org/0000-0003-2433-8404

http://orcid.org/0000-0002-7148-7616

http://orcid.org/0000-0002-1630-6210

http://orcid.org/0000-0002-2682-9736

http://orcid.org/0000-0002-9519-0059

http://orcid.org/0000-0003-3251-1086

http://orcid.org/0000-0001-6649-4128

http://orcid.org/0000-0002-1439-0930

http://orcid.org/0000-0002-1544-4910

http://orcid.org/0000-0003-0131-5699

http://orcid.org/0000-0003-2475-9727

10.1136/neurintsurg-2022-018694

The Woven EndoBridge (WEB) device has Food and Drug Administration approval for treatment of wide-necked intracranial bifurcation aneurysms. The WEB device has been shown to result in adequate occlusion in bifurcation aneurysms overall, but its usefulness in the individual bifurcation locations has been evaluated separately only in few case series, which were limited by small sample sizes. To compare angiographic and clinical outcomes after treatment of bifurcation aneurysms at various locations, including anterior communicating artery (AComA), anterior cerebral artery (ACA) bifurcation distal to AComA, basilar tip, internal carotid artery (ICA) bifurcation, and middle cerebral artery (MCA) bifurcation aneurysms using the WEB device. A retrospective cohort analysis was conducted at 22 academic institutions worldwide to compare treatment outcomes of patients with intracranial bifurcation aneurysms using the WEB device. Data include patient and aneurysm characteristics, procedural details, angiographic and functional outcomes, and complications. A total of 572 aneurysms were included. MCA (36%), AComA (35.7%), and basilar tip (18.9%) aneurysms were most common. The rate of adequate aneurysm occlusion was significantly higher for basilar tip (91.6%) and ICA bifurcation (96.7%) aneurysms and lower for ACA bifurcation (71.4%) and AComA (80.6%) aneurysms (p=0.04). To our knowledge, this is the most extensive study to date that compares the treatment of different intracranial bifurcation aneurysms using the WEB device. Basilar tip and ICA bifurcation aneurysms showed significantly higher rates of aneurysm occlusion than other locations.

link

Journal of Neurointerventional Surgery 2022; neurintsurg-2022-018694

Journal of Neurointerventional Surgery