Please use this identifier to cite or link to this item:
https://ahro.austin.org.au/austinjspui/handle/1/28913| Title: | Gut microbiome signatures and host colonization with multidrug-resistant bacteria. | Austin Authors: | Isles, Nicole S;Mu, Andre;Kwong, Jason C ;Howden, Benjamin P ;Stinear, Timothy P | Affiliation: | Microbiological Diagnostic Unit Public Health Laboratory, The University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Victoria, 3000, Australia.. Molecular and Systems Physiology Laboratory, The Salk Institute for Biological Studies, La Jolla, CA 92037, USA.. Department of Microbiology and Immunology, The University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Victoria, 3000, Australia.. Doherty Applied Microbial Genomics, The University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Victoria, 3000, Australia.. Department of Medicine, The University of Melbourne, Melbourne, Australia.. Infectious Diseases Gene Expression Laboratory, The Salk Institute for Biological Studies, La Jolla, CA 92037, USA.. NOMIS Center for Immunobiology and Microbial Pathogenesis, The Salk Institute for Biological Studies, La Jolla, CA 92037, USA.. |
Issue Date: | 18-Feb-2022 | Date: | 2022 | Publication information: | Trends in Microbiology 2022; 30(9): 853-865 | Abstract: | The human gut is host to a diverse range of microorganisms that offer protection against colonization by multidrug-resistant bacteria. Antibiotic use, medications, health conditions, and lifestyle factors can alter the composition of the gut microbiota in such a way that results in loss of colonization resistance and increased susceptibility to invading pathogenic antibiotic-resistant bacteria. Therapeutics aiming to restore a diverse and protective microbiome are fast advancing. In this review, we focus on the compositional changes within the gut microbiome that are associated with colonization resistance and discuss their use as potential targets for therapeutics or diagnostics. | URI: | https://ahro.austin.org.au/austinjspui/handle/1/28913 | DOI: | 10.1016/j.tim.2022.01.013 | ORCID: | 0000-0002-6298-7942 0000-0003-0237-1473 |
Journal: | Trends in microbiology | PubMed URL: | 35184972 | PubMed URL: | https://pubmed.ncbi.nlm.nih.gov/35184972/ | Type: | Journal Article | Subjects: | colonization resistance microbiome multidrug-resistant organism (MDRO) |
| Appears in Collections: | Journal articles |
Show full item record
Items in AHRO are protected by copyright, with all rights reserved, unless otherwise indicated.