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https://ahro.austin.org.au/austinjspui/handle/1/28041| Title: | Outcomes of non-myeloablative allogeneic stem cell transplant in older patients with acute myeloid leukaemia in first remission. | Austin Authors: | Nguyen, Phillip C;Manos, Kate ;Fong, Chun Y;Schwarer, Anthony P ;Tiong, Ing S ;Wei, Andrew H;Kliman, David;Curtis, David J | Affiliation: | Department of Clinical Haematology, Alfred Health, Melbourne, Victoria, Australia Australian Centre for Blood Diseases, Monash University, Melbourne, Victoria, Australia Department of Clinical Haematology, Box Hill Hospital, Melbourne, Victoria, Australia Clinical Haematology |
Issue Date: | 2021 | Publication information: | Internal medicine journal 2021; 51(11): 1954-1958 | Abstract: | The benefits of non-myeloablative stem cell transplant in older patients with acute myeloid leukaemia are unclear. We compare the long-term outcomes of this regimen in those aged 55-65 years in first remission with a chemotherapy only cohort that achieved durable morphologic remission. Five-year overall survival was similar (32% vs 33%, P = 0.90), as was relapse-free survival (23% vs 20%, P = 0.37). There was a trend for decreased relapse that was balanced against increased non-relapse mortality with transplantation. | URI: | https://ahro.austin.org.au/austinjspui/handle/1/28041 | DOI: | 10.1111/imj.15564 | ORCID: | 0000-0002-6238-0681 0000-0001-5773-103X 0000-0001-7417-4343 0000-0002-7514-3298 0000-0002-2020-0275 0000-0001-9497-0996 |
Journal: | Internal Medicine Journal | PubMed URL: | 34796631 | PubMed URL: | 10.1111/imj.15564 Abstract | Type: | Journal Article | Subjects: | acute myeloid leukemia consolidation chemotherapy elderly haemopoietic stem cell transplantation relapse survival |
| Appears in Collections: | Journal articles |
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