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Title: Antiplatelet Drugs for Neurointerventions: Part 2 Clinical Applications.
Austin Authors: Pearce, Samuel;Maingard, Julian T;Kuan Kok, Hong;Barras, Christen D;Russell, Jeremy H ;Hirsch, Joshua A;Chandra, Ronil V;Jhamb, Ash;Thijs, Vincent N ;Brooks, Mark;Asadi, Hamed 
Affiliation: Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA
Department of Radiology, Western Health, 160 Gordon St, 3011, Footscray, Victoria, Australia
Interventional Neuroradiology Unit, Monash Imaging, Monash Health, Melbourne, Victoria, Australia
School of Medicine, Faculty of Health, Deakin University, Waurn Ponds, Victoria, Australia
Interventional Radiology Service, Northern Health Radiology, Melbourne, Victoria, Australia
South Australian Health and Medical Research Institute, Adelaide, South Australia, Australia
School of Medicine, The University of Adelaide, Adelaide, South Australia, Australia
Department of Imaging, Monash University, Melbourne, Victoria, Australia
Interventional Neuroradiology, St Vincent's Hospital, Melbourne, Victoria, Australia
The Florey Institute of Neuroscience and Mental Health
School of Medicine, University of Melbourne, Melbourne, Victoria, Australia
Issue Date: Sep-2021
Date: 2021-03-01
Publication information: Clinical Neuroradiology 2021; 31(3): 545-558
Abstract: Endovascular techniques have expanded to include balloon and stent-assistance, flow diversion and individualized endovascular occlusion devices, to widen the treatment spectrum for more complex aneurysm morphologies. While usually well-tolerated by patients, endovascular treatment of intracranial aneurysms carries the risk of complications, with procedure-related ischemic complications being the most common. Several antiplatelet agents have been studied in a neurointerventional setting for both prophylaxis and in the setting of intraprocedural thrombotic complications. Knowledge of these antiplatelet agents, evidence for their use and common dosages is important for the practicing neurointerventionist to ensure the proper application of these agents.Part one of this two-part review focused on basic platelet physiology, pharmacology of common antiplatelet medications and future directions and therapies. Part two focuses on clinical applications and evidence based therapeutic regimens.
DOI: 10.1007/s00062-021-00997-4
Journal: Clinical Neuroradiology
PubMed URL: 33646319
Type: Journal Article
Subjects: Antiplatelets
Interventional radiology
Appears in Collections:Journal articles

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