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Title: Health economic implications of postoperative complications following liver resection surgery: a systematic review.
Austin Authors: Cosic, Luka ;Ma, Ronald ;Churilov, Leonid ;Nikfarjam, Mehrdad ;Christophi, Christopher ;Weinberg, Laurence 
Affiliation: Department of Surgery, Austin Health, The University of Melbourne, Heidelberg, Victoria, Australia
Department of Anaesthesia, Austin Health, Heidelberg, Victoria, Australia
Department of Finance, Austin Health, Heidelberg, Victoria, Australia
The Florey Institute of Neuroscience and Mental Health, Melbourne, Victoria, Australia
Issue Date: Dec-2019 2019-05-13
Publication information: ANZ Journal of Surgery 2019; 89(12): 1561-1566
Abstract: Limited data exists concerning the health economics of liver resection, with even less information on the costs emerging from complications, despite this remaining an important target from a health economic perspective. Our objective was to describe the financial burden of complications following liver resection. We conducted a systematic search and included studies reporting resource use of in-hospital complications during the index liver resection admission. All indications for liver resection were considered. All techniques were considered. Data was collected using a data extraction table and a narrative synthesis was performed. We identified 12 eligible articles. There was considerable heterogeneity in study designs, patient populations and outcome definitions. We found weak evidence of increased costs associated with major liver resection compared to minor resections. We found robust evidence supporting the increasing economic burden arising from complications after liver resection. Acceptable evidence for increased cost due to the presence and grade of complication was found. Strong evidence concerning the association of length of stay with costs was demonstrated. The presence and grade of complications increase hospital cost across diverse settings. The costing methodology should be transparent and complication grading systems should be consistent in future studies.
DOI: 10.1111/ans.15213
ORCID: 0000-0003-2860-0641
Journal: ANZ Journal of Surgery
PubMed URL: 31083782
Type: Journal Article
Subjects: costs and cost analysis
hospital cost
post-operative complication
Appears in Collections:Journal articles

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