Austin Health

Title
A review on the management of cerebral vasospasm following aneurysmal subarachnoid haemorrhage.
Publication Date
2019-06
Author(s)
Li, Kenny
Barras, Christen D
Chandra, Ronil V
Kok, Hong Kuan
Maingard, Julian T
Carter, Nicole S
Russell, Jeremy H
Lai, Leon
Brooks, Duncan Mark
Asadi, Hamed
Subject
Aneurysmal subarachnoid haemorrhage
delayed cerebral ischaemia
delayed ischaemic neurologic deficits
endovascular
intra-arterial vasodilator
transluminal balloon angioplasty
vasospasm
Type of document
Journal Article
OrcId
0000-0001-8958-2411
0000-0003-2475-9727
DOI
10.1016/j.wneu.2019.03.083
Abstract
Despite decades of research, cerebral vasospasm (CV) continues to account for high morbidity and mortality in patients who survive their initial aneurysm subarachnoid haemorrhage (aSAH). To define the scope of the problem and review key treatment strategies that have shaped the way cerebral vasospasm is managed in the contemporary era. A literature search of cerebral vasospasm management after aneurysmal subarachnoid haemorrhage was performed. Recent advances in neuroimaging have led to an improved detection of vasospasm, but established treatment guidelines including haemodynamic augmentation and interventional procedures remain highly variable among neurosurgical centres. Experimental research in SAH continues to identify novel targets for therapy. Proactive and preventative strategies such as oral nimodipine and endovascular rescue therapies can reduce the morbidity and mortality associated with CV.
Link
Citation
World Neurosurgery 2019; 126: 513-527
Jornal Title
World Neurosurgery

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