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Title: Reading on the right when there's nothing left? Probabilistic tractography reveals hemispheric asymmetry in pure alexia.
Austin Authors: Veldsman, Michele;Loetscher, Tobias;Wood, Amanda;Brodtmann, Amy 
Affiliation: Nuffield Department of Clinical Neuroscience, University of Oxford, Oxford, UK
Behavioural Neuroscience and Stroke Divisions, The Florey Institute for Neuroscience and Mental Health, Melbourne, Australia
School of Psychology, Social Work and Social Policy, University of South Australia, Adelaide, Australia
School of Life and Health Sciences & Aston Brain Centre, Aston University, Birmingham, UK
Clinical Sciences, Murdoch Childrens Research Institute, Melbourne, Australia
Austin Health, The University of Melbourne, Heidelberg, Victoria, Australia
Issue Date: 9-Aug-2017 2017-08
Publication information: Neurocase 2017; 23(3-4): 201-209
Abstract: We present a patient with reading inexpertise and right hemianopia following left posterior cerebral artery (PCA) stroke. We examine the extent of disruption to reading performance and the extent of white matter tract damage relative to a patient with more limited PCA infarction and isolated right hemianopia. We show white matter disconnection of the temporal occipital fusiform cortex in our pure alexia patient. Connectivity-based laterality indices revealed right hemisphere laterality in the alexia patient; this was not associated with improved reading function. We speculate that the degree of premorbid laterality may be a critical factor affecting the extent of reading dysfunction in alexia.
DOI: 10.1080/13554794.2017.1364775
ORCID: 0000-0003-2192-378X
Journal: Neurocase
PubMed URL: 28789579
Type: Journal Article
Subjects: Reading
diffusion tractography
Appears in Collections:Journal articles

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