Please use this identifier to cite or link to this item: http://ahro.austin.org.au/austinjspui/handle/1/16788
Title: Framing of mobility items: a source of poor agreement between preference-based health-related quality of life instruments in a population of individuals receiving assisted ventilation
Authors: Hannan, Liam M
Whitehurst, David GT
Bryan, Stirling
Road, Jeremy D
McDonald, Christine F
Berlowitz, David J
Howard, Mark E
Date of Publication: Jun-2017
Citation: Quality of Life Research 2017; 26(6): 1493-1505
Abstract: PURPOSE: To explore the influence of descriptive differences in items evaluating mobility on index scores generated from two generic preference-based health-related quality of life (HRQoL) instruments. METHODS: The study examined cross-sectional data from a postal survey of individuals receiving assisted ventilation in two state/province-wide home mechanical ventilation services, one in British Columbia, Canada and the other in Victoria, Australia. The Assessment of Quality of Life 8-dimension (AQoL-8D) and the EQ-5D-5L were included in the data collection. Graphical illustrations, descriptive statistics, and measures of agreement [intraclass correlation coefficients (ICCs) and Bland-Altman plots] were examined using index scores derived from both instruments. Analyses were performed on the full sample as well as subgroups defined according to respondents' self-reported ability to walk. RESULTS: Of 868 individuals receiving assisted ventilation, 481 (55.4%) completed the questionnaire. Mean index scores were 0.581 (AQoL-8D) and 0.566 (EQ-5D-5L) with 'moderate' agreement demonstrated between the two instruments (ICC = 0.642). One hundred fifty-nine (33.1%) reported level 5 ('I am unable to walk about') on the EQ-5D-5L Mobility item. The walking status of respondents had a marked influence on the comparability of index scores, with a larger mean difference (0.206) and 'slight' agreement (ICC = 0.386) observed when the non-ambulant subgroup was evaluated separately. CONCLUSIONS: This study provides further evidence that between-measure discrepancies between preference-based HRQoL instruments are related in part to the framing of mobility-related items. Longitudinal studies are necessary to determine the responsiveness of preference-based HRQoL instruments in cohorts that include non-ambulant individuals.
URI: http://ahro.austin.org.au/austinjspui/handle/1/16788
DOI: 10.1007/s11136-017-1510-z
ORCID: 0000-0003-2543-8722
PubMed URL: https://www.ncbi.nlm.nih.gov/pubmed/28255744
Type: Journal Article
Appears in Collections:Journal articles

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