Please use this identifier to cite or link to this item:
Title: Atypical small acinar proliferation and high grade prostatic intraepithelial neoplasia in the era of multi-parametric MRI: a contemporary review
Austin Authors: Manning, Todd G ;Cheung, Ernest ;Perera, Marlon ;Christidis, Daniel;O'Brien, Jonathan S;Mitchell, Catherine;Bolton, Damien M ;Lawrentschuk, Nathan
Affiliation: The Young Urology Researchers Organisation (YURO), Melbourne, Victoria, Australia
Department of Pathology, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia
Department of Surgical Oncology, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia
Olivia Newton-John Cancer Research Institute, Heidelberg, Victoria, Australia
Department of Surgery, Austin Health, The University of Melbourne, Heidelberg, Victoria, Australia
Issue Date: Sep-2017 2017-04-21
Publication information: Urology 2017; 107: 5-10
Abstract: Multiparametric Magnetic Resonance Imaging (mpMRI) has added to the armamentarium for the diagnosis and surveillance for organ confined prostate cancer. Atypical small acinar proliferation (ASAP) and high-grade prostatic intraepithelial neoplasia (HGPIN) are premalignant prostatic lesions. The management of such lesions remains contentious, and the addition of mpMRI introduces further uncertainty given its ability to pick up indolent lesions and its use in targeted biopsy. We aimed to perform a comprehensive review of current evidence regarding ASAP, HGPIN and mpMRI to ascertain a consensus for a current management algorithm.
DOI: 10.1016/j.urology.2017.04.021
ORCID: 0000-0001-5609-3769
PubMed URL:
Type: Journal Article
Subjects: ASAP
Atypical small acinar proliferation
High-grade prostatic intraepithelial neoplasia
Multiparametric Magnetic Resonance Imaging
Premalignant lesions
Appears in Collections:Journal articles

Show full item record

Google ScholarTM


Items in AHRO are protected by copyright, with all rights reserved, unless otherwise indicated.