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Title: Prostate Cancer - Double vision but solitary lesion
Austin Authors: Lim, Hui Yin;Perchyonok, Yuliya ;Fitt, Gregory J ;Lokan, Julie ;Wada, Morikatsu ;Fabinyi, Gavin C ;Azad, A;Cher, Lawrence M ;Gan, Hui K 
Affiliation: Department of Medical Oncology, Austin Health, Heidelberg, Victoria, Australia
Department of Radiology, Austin Health, Heidelberg, Victoria, Australia
Department of Anatomical Pathology, Austin Health, Heidelberg, Victoria, Australia
Radiation Oncology
Issue Date: 30-Apr-2014
Publication information: Journal of Case Reports and Studies 2014; 2(2): 201
Abstract: A 53 year old man with a background of castrate-sensitive prostate cancer on intermittent androgen deprivation therapy (ADT) presented with right sixth nerve palsy secondary to a solitary right petroclival lesion involving adjacent dura and bone. The clinical and imaging characteristics of the lesion were consistent with a number of differential diagnoses (including metastatic prostate cancer, meningioma and chondrosarcoma). The patient initially declined biopsy and ADT was recommenced but the lesion continued to enlarge despite an excellent biochemical response. A subsequent biopsy of the petroclival mass demonstrated a WHO grade I meningioma and the patient proceeded to have definitive stereotactic radiotherapy. This case illustrates an unusual solitary skull base lesion in a man with prostate cancer. Whilst bony metastases, usually multiple, in the skeleton are common, solitary skull or brain lesions should be investigated as alternate diagnoses are likely in such circumstance.
DOI: 10.15744/2348-9820.1.501
ORCID: 0000-0003-3476-8766
Journal: Journal of Case Reports and Studies
Type: Journal Article
Subjects: Metastasis
Prostate cancer
Petroclival lesion
Type of Clinical Study or Trial: Case Series and Case Reports
Appears in Collections:Journal articles

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