Please use this identifier to cite or link to this item: https://ahro.austin.org.au/austinjspui/handle/1/16577
Title: Dietary supplement use in older people attending memory clinics in Australia
Austin Authors: Cross, AJ;George, J;Woodward, Michael C;Ames, D;Brodaty, H;Elliott, Rohan A 
Affiliation: Centre for Medicine Use and Safety, Faculty of Pharmacy and Pharmaceutical Sciences, Monash University, Parkville, Victoria, Australia
Medical and Cognitive Research Unit, Austin Health, Heidelberg, Victoria, Australia
National Ageing Research Institute, Parkville, Victoria, Australia
University of Melbourne Academic Unit for Psychiatry of Old Age, St George’s Hospital, Kew, Victoria, Australia
Dementia Collaborative Research Centre, School of Psychiatry, University of NSW, Sydney, NSW, Australia
Center for Healthy Brain Aging, School of Psychiatry, University of NSW, Sydney, NSW, Australia
Pharmacy Department, Austin Health, Melbourne, Victoria, Australia
Issue Date: Jan-2017
Publication information: Journal of Nutrition, Health & Aging 2017; 21(1): 46-50
Abstract: BACKGROUND: Dietary supplement use is common in older adults. There has been limited research in people attending memory clinics. OBJECTIVES: To explore the use of dietary supplements in older people attending Australian memory clinics. DESIGN: Cross-sectional analysis of baseline data from the Prospective Research In MEmory clinics (PRIME) study. PARTICIPANTS: Community-dwelling older people who attended nine memory clinics and had a diagnosis of mild cognitive impairment (MCI) or dementia. MEASUREMENTS: Dietary supplement was defined as a product that contains one or more: vitamin, mineral, herb or other botanical, amino acid or other dietary substance. Non-prescribed supplement was defined as a supplement that is not usually prescribed by a medical practitioner. Polypharmacy was defined as use of five or more medications. RESULTS: 964 patients, mean age 77.6 years, were included. Dietary supplements were used by 550 (57.1%) patients; 353 (36.6%) used two or more. Non-prescribed supplements were used by 364 (36.8%) patients. Supplement use was associated with older age (OR: 1.12, 95% CI: 1.03-1.21), lower education level (OR: 1.53, 95% CI: 1.01-2.32) and a diagnosis of MCI rather than dementia (OR: 1.52, 95% CI: 1.05-2.21). Potential drug-supplement interactions were identified in 107 (11.1%) patients. Supplement users had increased prevalence of polypharmacy compared to non-users (80.5% vs. 48.1%, p<0.001). CONCLUSIONS: Dietary supplements, including non-prescribed supplements, were commonly used by people attending memory clinics. Supplement use increased the prevalence of polypharmacy and resulted in potential supplement-drug interactions. Further research is required to assess the clinical outcomes of supplement use.
URI: http://ahro.austin.org.au/austinjspui/handle/1/16577
DOI: 10.1007/s12603-016-0742-x
PubMed URL: https://pubmed.ncbi.nlm.nih.gov/27999849
Type: Journal Article
Appears in Collections:Journal articles

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