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dc.contributor.authorCross, AJ-
dc.contributor.authorGeorge, J-
dc.contributor.authorWoodward, Michael C-
dc.contributor.authorAmes, D-
dc.contributor.authorBrodaty, H-
dc.contributor.authorElliott, Rohan A-
dc.identifier.citationJournal of Nutrition, Health & Aging 2017; 21(1): 46-50en_US
dc.description.abstractBACKGROUND: Dietary supplement use is common in older adults. There has been limited research in people attending memory clinics. OBJECTIVES: To explore the use of dietary supplements in older people attending Australian memory clinics. DESIGN: Cross-sectional analysis of baseline data from the Prospective Research In MEmory clinics (PRIME) study. PARTICIPANTS: Community-dwelling older people who attended nine memory clinics and had a diagnosis of mild cognitive impairment (MCI) or dementia. MEASUREMENTS: Dietary supplement was defined as a product that contains one or more: vitamin, mineral, herb or other botanical, amino acid or other dietary substance. Non-prescribed supplement was defined as a supplement that is not usually prescribed by a medical practitioner. Polypharmacy was defined as use of five or more medications. RESULTS: 964 patients, mean age 77.6 years, were included. Dietary supplements were used by 550 (57.1%) patients; 353 (36.6%) used two or more. Non-prescribed supplements were used by 364 (36.8%) patients. Supplement use was associated with older age (OR: 1.12, 95% CI: 1.03-1.21), lower education level (OR: 1.53, 95% CI: 1.01-2.32) and a diagnosis of MCI rather than dementia (OR: 1.52, 95% CI: 1.05-2.21). Potential drug-supplement interactions were identified in 107 (11.1%) patients. Supplement users had increased prevalence of polypharmacy compared to non-users (80.5% vs. 48.1%, p<0.001). CONCLUSIONS: Dietary supplements, including non-prescribed supplements, were commonly used by people attending memory clinics. Supplement use increased the prevalence of polypharmacy and resulted in potential supplement-drug interactions. Further research is required to assess the clinical outcomes of supplement use.en_US
dc.titleDietary supplement use in older people attending memory clinics in Australiaen_US
dc.typeJournal Articleen_US
dc.identifier.journaltitleJournal of Nutrition, Health & Agingen_US
dc.identifier.affiliationCentre for Medicine Use and Safety, Faculty of Pharmacy and Pharmaceutical Sciences, Monash University, Parkville, Victoria, Australiaen_US
dc.identifier.affiliationMedical and Cognitive Research Unit, Austin Health, Heidelberg, Victoria, Australiaen_US
dc.identifier.affiliationNational Ageing Research Institute, Parkville, Victoria, Australiaen_US
dc.identifier.affiliationUniversity of Melbourne Academic Unit for Psychiatry of Old Age, St George’s Hospital, Kew, Victoria, Australiaen_US
dc.identifier.affiliationDementia Collaborative Research Centre, School of Psychiatry, University of NSW, Sydney, NSW, Australiaen_US
dc.identifier.affiliationCenter for Healthy Brain Aging, School of Psychiatry, University of NSW, Sydney, NSW, Australiaen_US
dc.identifier.affiliationPharmacy Department, Austin Health, Melbourne, Victoria, Australiaen_US
dc.type.austinJournal Articleen_US
item.fulltextNo Fulltext-
item.openairetypeJournal Article-
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