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Title: The effects of resistance training on muscle strength, quality of life and aerobic capacity in patients with chronic heart failure - a meta-analysis
Austin Authors: Giuliano, Catherine;Karahalios, Amalia;Neil, Christopher;Allen, Jason;Levinger, Itamar 
Affiliation: Clinical Exercise Science Research Program, Institute of Sport, Exercise and Active Living (ISEAL), Victoria University, Melbourne, Australia
Western Health, Melbourne, Victoria, Australia
Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Victoria, Australia
Department of Cardiology, Austin Health, Heidelberg, Victoria, Australia
Department of Medicine - Western Precinct at the University of Melbourne, Victoria, Australia
Issue Date: 15-Jan-2017 2016-11-07
Publication information: International Journal of Cardiology 2017; 227: 413-423
Abstract: BACKGROUND: Resistance training (RT) has been utilised to target muscle dysfunction associated with Chronic Heart Failure (CHF). However, there is limited meta-analysis evidence to support its use as a standalone therapy. This meta-analysis examined the effects of RT on muscle strength (one repetition maximum, 1RM and Peak Torque), aerobic capacity (VO2peak and 6min walk distance) and quality of life (QoL) in patients with CHF. METHODS: We searched Medline, EMBASE, Cochrane and CINAHL for studies published up to July 2016, combining terms related to the population (eg, heart failure, CHF) with terms for the intervention (eg, resistance, strength training) and the outcomes (eg, QoL, VO2peak,strength, aerobic capacity). RESULTS: Ten studies including 240 participants were included in our meta-analysis (aged 48-76years, Ejection Fraction 18-37%). Training duration ranged from 8 to 24weeks and intensity up to 80% of 1RM. RT increased 1RM (standardised change score=0.60; 95% Confidence Interval: 0.43, 0.77) but not strength measured via peak torque at 60°/s-1 and 180°/s-1. RT increased VO2peak (CSMD: 2.71ml/kg/min; 1.96, 3.45) and QoL (CSMD: -5.71; -9.85, -1.56). CONCLUSION: RT as a single intervention can increase muscle strength, aerobic capacity and QoL in patients with CHF and may offer an alternative approach, particularly for those unable to participate in aerobic training. The effect of RT on muscle strength is mainly during slow controlled movements and not during rapid movements. Older adults and patients with advanced CHF are underrepresented in RT trials and future studies should seek to optimise their inclusion.
DOI: 10.1016/j.ijcard.2016.11.023
PubMed URL:
Type: Journal Article
Subjects: Aerobic capacity
Chronic heart failure
Muscle strength
Quality of life
Systematic review
Type of Clinical Study or Trial: Reviews/Systematic Reviews
Appears in Collections:Journal articles

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