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https://ahro.austin.org.au/austinjspui/handle/1/16316| Title: | MRI correlates of general intelligence in neurotypical adults | Austin Authors: | Malpas, Charles B;Genc, Sila;Saling, Michael M ;Velakoulis, Dennis;Desmond, Patricia M;O’Brien, Terence J | Affiliation: | Melbourne Brain Centre, Royal Melbourne Hospital, Parkville, Victoria, Australia Melbourne School of Psychological Sciences, University of Melbourne, Parkville, Victoria, Australia Department of Medicine, Royal Melbourne Hospital, The University of Melbourne, Parkville, Victoria, Australia Developmental Imaging, Murdoch Children’s Research Institute, Victoria, Australia Department of Radiology, University of Melbourne, Victoria, Australia Department of Neuropsychology, Austin Health, Heidelberg, Victoria, Australia Melbourne Neuropsychiatry Centre, Royal Melbourne Hospital, Parkville, Victoria, Australia Department of Psychiatry, University of Melbourne, Victoria, Australia Department of Medical Imaging, Royal Melbourne Hospital, Parkville, Victoria, Australia |
Issue Date: | Feb-2016 | Date: | 2015-10-09 | Publication information: | Journal of Clinical Neuroscience 2016; 24: 128-134 | Abstract: | There is growing interest in the neurobiological substrate of general intelligence. Psychometric estimates of general intelligence are reduced in a range of neurological disorders, leading to practical application as sensitive, but non-specific, markers of cerebral disorder. This study examined estimates of general intelligence in neurotypical adults using diffusion tensor imaging and resting-state functional connectivity analysis. General intelligence was related to white matter organisation across multiple brain regions, confirming previous work in older healthy adults. We also found that variation in general intelligence was related to a large functional sub-network involving all cortical lobes of the brain. These findings confirm that individual variance in general intelligence is related to diffusely represented brain networks. | URI: | https://ahro.austin.org.au/austinjspui/handle/1/16316 | DOI: | 10.1016/j.jocn.2015.07.012 | Journal: | Journal of Clinical Neuroscience | PubMed URL: | https://pubmed.ncbi.nlm.nih.gov/26455546 | Type: | Journal Article | Subjects: | Diffusion MRI Functional connectivity Intelligence Brain Resting state White matter |
| Appears in Collections: | Journal articles |
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