Please use this identifier to cite or link to this item: https://ahro.austin.org.au/austinjspui/handle/1/16316
Title: MRI correlates of general intelligence in neurotypical adults
Austin Authors: Malpas, Charles B;Genc, Sila;Saling, Michael M ;Velakoulis, Dennis;Desmond, Patricia M;O’Brien, Terence J
Affiliation: Melbourne Brain Centre, Royal Melbourne Hospital, Parkville, Victoria, Australia
Melbourne School of Psychological Sciences, University of Melbourne, Parkville, Victoria, Australia
Department of Medicine, Royal Melbourne Hospital, The University of Melbourne, Parkville, Victoria, Australia
Developmental Imaging, Murdoch Children’s Research Institute, Victoria, Australia
Department of Radiology, University of Melbourne, Victoria, Australia
Department of Neuropsychology, Austin Health, Heidelberg, Victoria, Australia
Melbourne Neuropsychiatry Centre, Royal Melbourne Hospital, Parkville, Victoria, Australia
Department of Psychiatry, University of Melbourne, Victoria, Australia
Department of Medical Imaging, Royal Melbourne Hospital, Parkville, Victoria, Australia
Issue Date: Feb-2016
metadata.dc.date: 2015-10-09
Publication information: Journal of Clinical Neuroscience 2016; 24: 128-134
Abstract: There is growing interest in the neurobiological substrate of general intelligence. Psychometric estimates of general intelligence are reduced in a range of neurological disorders, leading to practical application as sensitive, but non-specific, markers of cerebral disorder. This study examined estimates of general intelligence in neurotypical adults using diffusion tensor imaging and resting-state functional connectivity analysis. General intelligence was related to white matter organisation across multiple brain regions, confirming previous work in older healthy adults. We also found that variation in general intelligence was related to a large functional sub-network involving all cortical lobes of the brain. These findings confirm that individual variance in general intelligence is related to diffusely represented brain networks.
URI: http://ahro.austin.org.au/austinjspui/handle/1/16316
DOI: 10.1016/j.jocn.2015.07.012
PubMed URL: https://pubmed.ncbi.nlm.nih.gov/26455546
Type: Journal Article
Subjects: Diffusion MRI
Functional connectivity
Intelligence
Brain
Resting state
White matter
Appears in Collections:Journal articles

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