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Title: Plasma prolactin and fluphenazine concentrations in patients receiving fluphenazine decanoate: stability over injection intervals.
Austin Authors: Norman, Trevor R ;Marriott, P F;Kimber, N M;Burrows, Graham D
Affiliation: Department of Psychiatry, University of Melbourne, Austin Hospital, Heidelberg, Victoria, Australia
Issue Date: 1-Oct-1987
Publication information: International Clinical Psychopharmacology; 2(4): 299-305
Abstract: Plasma prolactin and fluphenazine concentrations were measured in a group of 17 patients (9 males, 8 females) with schizophrenia who were receiving chronic treatment with fluphenazine decanoate. Neither measure was significantly correlated with clinical effect, as measured by the Brief Psychiatric Rating Scale, at any of the 5 pre-injection times examined. None of the measures showed statistically significant (P greater than 0.05; MANOVA) variations with time. Neither measure showed a significant correlation with the dose (expressed as mg/kg) of fluphenazine. The implications of the study for monitoring chronic treatment of schizophrenia are discussed.
Gov't Doc #: 3693869
Journal: International clinical psychopharmacology
Type: Journal Article
Subjects: Adult
Fluphenazine.analogs & derivatives.blood.therapeutic use
Middle Aged
Schizophrenia.blood.drug therapy
Appears in Collections:Journal articles

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