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Title: | Plasma prolactin and fluphenazine concentrations in patients receiving fluphenazine decanoate: stability over injection intervals. | Austin Authors: | Norman, Trevor R ;Marriott, P F;Kimber, N M;Burrows, Graham D | Affiliation: | Department of Psychiatry, University of Melbourne, Austin Hospital, Heidelberg, Victoria, Australia | Issue Date: | 1-Oct-1987 | Publication information: | International Clinical Psychopharmacology; 2(4): 299-305 | Abstract: | Plasma prolactin and fluphenazine concentrations were measured in a group of 17 patients (9 males, 8 females) with schizophrenia who were receiving chronic treatment with fluphenazine decanoate. Neither measure was significantly correlated with clinical effect, as measured by the Brief Psychiatric Rating Scale, at any of the 5 pre-injection times examined. None of the measures showed statistically significant (P greater than 0.05; MANOVA) variations with time. Neither measure showed a significant correlation with the dose (expressed as mg/kg) of fluphenazine. The implications of the study for monitoring chronic treatment of schizophrenia are discussed. | Gov't Doc #: | 3693869 | URI: | https://ahro.austin.org.au/austinjspui/handle/1/13005 | Journal: | International clinical psychopharmacology | URL: | https://pubmed.ncbi.nlm.nih.gov/3693869 | Type: | Journal Article | Subjects: | Adult Female Fluphenazine.analogs & derivatives.blood.therapeutic use Humans Male Middle Aged Prolactin.blood Schizophrenia.blood.drug therapy |
Appears in Collections: | Journal articles |
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