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Title: Clinical utility of exercise training in heart failure with reduced and preserved ejection fraction.
Austin Authors: Asrar Ul Haq, Muhammad;Goh, Cheng Yee;Levinger, Itamar ;Wong, Chiew;Hare, David L 
Affiliation: Austin Health, Heidelberg, Victoria, Australia, Australia
Institute of Sport, Exercise and Active Living (ISEAL), College of Sport and Exercise Science, Victoria University, Melbourne, Australia
Northern Heart, The Northern Hospital, Melbourne, Victoria, Australia
; University of Melbourne, Melbourne, Victoria, Australia
; Austin Health, Heidelberg, Victoria, Australia, Australia
Issue Date: 9-Feb-2015
Publication information: Clinical Medicine Insights. Cardiology 2015; 9(): 1-9
Abstract: Reduced exercise tolerance is an independent predictor of hospital readmission and mortality in patients with heart failure (HF). Exercise training for HF patients is well established as an adjunct therapy, and there is sufficient evidence to support the favorable role of exercise training programs for HF patients over and above the optimal medical therapy. Some of the documented benefits include improved functional capacity, quality of life (QoL), fatigue, and dyspnea. Major trials to assess exercise training in HF have, however, focused on heart failure with reduced ejection fraction (HFREF). At least half of the patients presenting with HF have heart failure with preserved ejection fraction (HFPEF) and experience similar symptoms of exercise intolerance, dyspnea, and early fatigue, and similar mortality risk and rehospitalization rates. The role of exercise training in the management of HFPEF remains less clear. This article provides a brief overview of pathophysiology of reduced exercise tolerance in HFREF and heart failure with preserved ejection fraction (HFPEF), and summarizes the evidence and mechanisms by which exercise training can improve symptoms and HF. Clinical and practical aspects of exercise training prescription are also discussed.
Gov't Doc #: 25698883
DOI: 10.4137/CMC.S21372
ORCID: 0000-0001-9554-6556
PubMed URL: 25698883
Type: Journal Article
Subjects: HFPEF
heart failure
Appears in Collections:Journal articles

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