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Title: Northern Territory Perspectives on Heart Failure With Comorbidities - Understanding Trial Validity and Exploring Collaborative Opportunities to Broaden the Evidence Base.
Austin Authors: Iyngkaran, P;Majoni, W;Cass, Alan;Sanders, Prashanthan;Ronco, Claudio;Brady, S;Kangaharan, N;Ilton, M;Hare, David L ;Thomas, Merlin C
Affiliation: Centre for Heart Rhythm Disorders (CHRD), South Australian Health and Medical Research Institute (SAHMRI), University of Adelaide and Royal Adelaide Hospital, Adelaide, Australia
Baker IDI Heart and Diabetes Institute, Central Melbourne Victoria 3004, Australia
Royal Darwin Hospital, Flinders University, Darwin Private Hospital, Tiwi, NT 0811
Royal Darwin Hospital, Department of Nephrology Division of Medicine
Menzies School of Health Research, Casuarina NT 0811
Department of Nephrology Dialysis & Transplantation, International Renal Research Institute (IRRIV) San Bortolo Hospital, Vicenza, Italy
Alice Springs Hospital, Alice Springs NT 0871
Division of Medicine, Royal Darwin Hospital, Royal Darwin Hospital, Tiwi, NT 0810
Royal Darwin Hospital, Royal Darwin Hospital, Tiwi, NT 0810
Coordinator, Cardiovascular Research, University of Melbourne; Director of Heart Failure Services, Austin Health, Vic 3084
Issue Date: 24-Dec-2014
Publication information: Heart, Lung & Circulation 2014; 24(6): 536-43
Abstract: Congestive Heart Failure (CHF) is an ambulatory care sensitive condition, associated with significant morbidity and mortality, rarely with cure. Outpatient based pharmacological management represents the main and most important aspect of care, and is usually lifelong. This narrative styled opinion review looks at the pharmacological agents recommended in the guidelines in context of the Northern Territory (NT) of Australia. We explore the concept of validity, a term used to describe the basis of standardising a particular trial or study and the population to which it is applicable. We aim to highlight the problems of the current guidelines based approach. We also present alternatives that could utilise the core principles from major trials, while incorporating regional considerations, which could benefit clients living in the NT and remote Australia.
Gov't Doc #: 25637942
DOI: 10.1016/j.hlc.2014.12.007
ORCID: 0000-0001-9554-6556
Journal: Heart, Lung & Circulation
PubMed URL: 25637942
Type: Journal Article
Subjects: Guidelines
Heart Failure
Indigenous Australians
Appears in Collections:Journal articles

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