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Title: | Northern Territory Perspectives on Heart Failure With Comorbidities - Understanding Trial Validity and Exploring Collaborative Opportunities to Broaden the Evidence Base. | Austin Authors: | Iyngkaran, P;Majoni, W;Cass, Alan;Sanders, Prashanthan;Ronco, Claudio;Brady, S;Kangaharan, N;Ilton, M;Hare, David L ;Thomas, Merlin C | Affiliation: | Centre for Heart Rhythm Disorders (CHRD), South Australian Health and Medical Research Institute (SAHMRI), University of Adelaide and Royal Adelaide Hospital, Adelaide, Australia Baker IDI Heart and Diabetes Institute, Central Melbourne Victoria 3004, Australia Royal Darwin Hospital, Flinders University, Darwin Private Hospital, Tiwi, NT 0811 Royal Darwin Hospital, Department of Nephrology Division of Medicine Menzies School of Health Research, Casuarina NT 0811 Department of Nephrology Dialysis & Transplantation, International Renal Research Institute (IRRIV) San Bortolo Hospital, Vicenza, Italy Alice Springs Hospital, Alice Springs NT 0871 Division of Medicine, Royal Darwin Hospital, Royal Darwin Hospital, Tiwi, NT 0810 Royal Darwin Hospital, Royal Darwin Hospital, Tiwi, NT 0810 Coordinator, Cardiovascular Research, University of Melbourne; Director of Heart Failure Services, Austin Health, Vic 3084 |
Issue Date: | 24-Dec-2014 | Publication information: | Heart, Lung & Circulation 2014; 24(6): 536-43 | Abstract: | Congestive Heart Failure (CHF) is an ambulatory care sensitive condition, associated with significant morbidity and mortality, rarely with cure. Outpatient based pharmacological management represents the main and most important aspect of care, and is usually lifelong. This narrative styled opinion review looks at the pharmacological agents recommended in the guidelines in context of the Northern Territory (NT) of Australia. We explore the concept of validity, a term used to describe the basis of standardising a particular trial or study and the population to which it is applicable. We aim to highlight the problems of the current guidelines based approach. We also present alternatives that could utilise the core principles from major trials, while incorporating regional considerations, which could benefit clients living in the NT and remote Australia. | Gov't Doc #: | 25637942 | URI: | https://ahro.austin.org.au/austinjspui/handle/1/12608 | DOI: | 10.1016/j.hlc.2014.12.007 | ORCID: | 0000-0001-9554-6556 | Journal: | Heart, Lung & Circulation | PubMed URL: | 25637942 | Type: | Journal Article | Subjects: | Guidelines Heart Failure Indigenous Australians Remote Rural Therapeutics |
Appears in Collections: | Journal articles |
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