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Title: Long-term efficacy of a tele-health intervention for acute coronary syndrome patients with depression: 12-month results of the MoodCare randomized controlled trial.
Austin Authors: O'Neil, Adrienne;Taylor, Barr;Hare, David L ;Sanderson, Kristy;Cyril, Sheila;Venugopal, Kamalesh;Chan, Bianca;Atherton, John J;Hawkes, Anna;Walters, Darren L;Oldenburg, Brian
Institutional Author: on behalf of the MoodCare Investigator Team
Affiliation: Department of Cardiology, Austin Health, Heidelberg, Victoria, Australia
Department of Medicine, University of Queensland, Queensland, Australia
Department of Cardiology, The Price Charles Hospital, Queensland, Australia
School of Medicine, Deakin University, Victoria, Australia
Department of Psychiatry, Stanford University, CA, USA
Menzies Research Institute Tasmania, University of Tasmania, Australia
School of Public Health and Preventive Medicine, Monash University, Victoria, Australia
Institute for Safety, Compensation and Recovery Research, Monash University, Victoria, Australia
School of Public Health and Social Work, Queensland University of Technology, Queensland, Australia
University of Melbourne, Victoria, Australia
Department of Cardiology, The Royal Brisbane and Women's Hospital, Queensland, Australia
School of Public Health and Preventive Medicine, Monash University, Victoria, Australia School of Population and Global Health, University of Melbourne, Melbourne.
Issue Date: 2015
Date: 2014-08-26
Publication information: European Journal of Preventive Cardiology 2015; 22(9): 1111-1120
Abstract: Depression is common after a cardiac event; however it often remains untreated. Previously, we reported the efficacy and feasibility of a 6-month tele-health programme (MoodCare), which integrates depression management into a cardiovascular disease (CVD) risk reduction programme for Acute Coronary Syndrome (ACS) patients with low mood. Here, we evaluate the long-term efficacy of the programme at 12-month follow-up.A two-arm, parallel, randomized design to compare the long-term effects of 'MoodCare' (n = 61) to usual care (UC) (n = 60) at 12 months.121 ACS patients recruited from six hospitals in Victoria and Brisbane, Australia were randomized to a telephone-delivered cognitive behavioural therapy and risk-reduction programme or usual medical care. Mixed-model repeated measurements (MMRM) analysis was applied with results expressed as estimated marginal mean changes in depression and health-related quality of life (HRQOL) outcomes by group.After 12 months, treatment effects were observed for those with major depressive disorder (MDD) for PHQ-9 depression (MoodCare: mean score: 6.5; 95% CI: 4.9-8.0 versus UC: 9.3; 95% CI: 7.7-10.9, p = 0.012)) and SF-12 mental health scores (MoodCare: 42.5; 95% CI: 39.8-45.2 versus UC: 36.8; 95% CI: 34.1-39.6, p = 0.005). No beneficial treatment effects were observed in those with no MDD at baseline.After 12 months, MoodCare was superior to UC for improving mental health outcomes for those with a clinical diagnosis of major depression. Our findings support the implementation of depression-based interventions for cardiac patients with a clinical diagnosis of depression and provide evidence of longer term efficacy to one year.
Gov't Doc #: 25159700
DOI: 10.1177/2047487314547655
ORCID: 0000-0001-9554-6556
Journal: European journal of preventive cardiology
PubMed URL: 25159700
Type: Journal Article
Subjects: Depression
acute coronary syndrome
cognitive behaviour therapy
Appears in Collections:Journal articles

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