Please use this identifier to cite or link to this item:
Title: Systematic review of non-invasive positive pressure ventilation for chronic respiratory failure.
Austin Authors: Hannan, Liam M ;Dominelli, Giulio S;Chen, Yi-Wen;Darlene Reid, W;Road, Jeremy
Affiliation: Institute for Breathing and Sleep, Austin Hospital, Heidelberg, Victoria, Australia
University of British Columbia, Department of Physical Therapy, Vancouver, British Columbia, Canada
University of Melbourne, Medicine, Dentistry and Health Sciences, Melbourne, Victoria, Australia
University of British Columbia, Respiratory Division and Department of Medicine, Vancouver, British Columbia, Canada
Issue Date: 20-Nov-2013
Publication information: Respiratory Medicine 2013; 108(2): 229-43
Abstract: This systematic review examined the effect of non-invasive positive pressure ventilation (NIPPV) on patient reported outcomes (PROs) and survival for individuals with or at risk of chronic respiratory failure (CRF).Randomised controlled trials (RCTs) and prospective non-randomised studies in those treated with NIPPV for CRF were identified from electronic databases, reference lists and grey literature. Diagnostic groups included in the review were amyotrophic lateral sclerosis/motor neuron disease (ALS/MND), Duchenne muscular dystrophy (DMD), restrictive thoracic disease (RTD) and obesity hypoventilation syndrome (OHS).Eighteen studies were included and overall study quality was weak. Those with ALS/MND had improved somnolence and fatigue as well as prolonged survival with NIPPV. For OHS, improvements in somnolence and fatigue, dyspnoea and sleep quality were demonstrated, while for RTD, measures of dyspnoea, sleep quality, physical function and health, mental and emotional health and social function improved. There was insufficient evidence to form conclusions regarding the effect of NIPPV for those with DMD.This review has demonstrated that NIPPV influences PROs differently depending on the underlying cause of CRF. These findings may provide assistance to patients and clinicians to determine the relative costs and benefits of NIPPV therapy and also highlight areas in need of further research.
Gov't Doc #: 24315469
DOI: 10.1016/j.rmed.2013.11.010
Journal: Respiratory medicine
Type: Journal Article
Subjects: Chronic respiratory failure
Non-invasive ventilation
Quality of life
Amyotrophic Lateral Sclerosis.complications.therapy
Chronic Disease
Muscular Dystrophy, Duchenne.complications.therapy
Obesity Hypoventilation Syndrome.complications.therapy
Positive-Pressure Respiration.methods
Prospective Studies
Randomized Controlled Trials as Topic
Respiratory Insufficiency.etiology.therapy
Treatment Outcome
Appears in Collections:Journal articles

Show full item record

Page view(s)

checked on Feb 7, 2023

Google ScholarTM


Items in AHRO are protected by copyright, with all rights reserved, unless otherwise indicated.