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dc.contributor.authorHannan, Liam Men
dc.contributor.authorDominelli, Giulio Sen
dc.contributor.authorChen, Yi-Wenen
dc.contributor.authorDarlene Reid, Wen
dc.contributor.authorRoad, Jeremyen
dc.identifier.citationRespiratory Medicine 2013; 108(2): 229-43en
dc.description.abstractThis systematic review examined the effect of non-invasive positive pressure ventilation (NIPPV) on patient reported outcomes (PROs) and survival for individuals with or at risk of chronic respiratory failure (CRF).Randomised controlled trials (RCTs) and prospective non-randomised studies in those treated with NIPPV for CRF were identified from electronic databases, reference lists and grey literature. Diagnostic groups included in the review were amyotrophic lateral sclerosis/motor neuron disease (ALS/MND), Duchenne muscular dystrophy (DMD), restrictive thoracic disease (RTD) and obesity hypoventilation syndrome (OHS).Eighteen studies were included and overall study quality was weak. Those with ALS/MND had improved somnolence and fatigue as well as prolonged survival with NIPPV. For OHS, improvements in somnolence and fatigue, dyspnoea and sleep quality were demonstrated, while for RTD, measures of dyspnoea, sleep quality, physical function and health, mental and emotional health and social function improved. There was insufficient evidence to form conclusions regarding the effect of NIPPV for those with DMD.This review has demonstrated that NIPPV influences PROs differently depending on the underlying cause of CRF. These findings may provide assistance to patients and clinicians to determine the relative costs and benefits of NIPPV therapy and also highlight areas in need of further research.en
dc.subject.otherChronic respiratory failureen
dc.subject.otherNon-invasive ventilationen
dc.subject.otherQuality of lifeen
dc.subject.otherAmyotrophic Lateral Sclerosis.complications.therapyen
dc.subject.otherChronic Diseaseen
dc.subject.otherMuscular Dystrophy, Duchenne.complications.therapyen
dc.subject.otherObesity Hypoventilation Syndrome.complications.therapyen
dc.subject.otherPositive-Pressure Respiration.methodsen
dc.subject.otherProspective Studiesen
dc.subject.otherRandomized Controlled Trials as Topicen
dc.subject.otherRespiratory Insufficiency.etiology.therapyen
dc.subject.otherTreatment Outcomeen
dc.titleSystematic review of non-invasive positive pressure ventilation for chronic respiratory failure.en
dc.typeJournal Articleen
dc.identifier.journaltitleRespiratory medicineen
dc.identifier.affiliationInstitute for Breathing and Sleep, Austin Hospital, Heidelberg, Victoria, Australiaen
dc.identifier.affiliationUniversity of British Columbia, Department of Physical Therapy, Vancouver, British Columbia, Canadaen
dc.identifier.affiliationUniversity of Melbourne, Medicine, Dentistry and Health Sciences, Melbourne, Victoria, Australiaen
dc.identifier.affiliationUniversity of British Columbia, Respiratory Division and Department of Medicine, Vancouver, British Columbia, Canadaen
dc.type.austinJournal Articleen
item.openairetypeJournal Article-
item.fulltextNo Fulltext-
item.cerifentitytypePublications- for Breathing and Sleep-
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