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Title: Depression and cardiovascular disease: a clinical review.
Austin Authors: Hare, David L ;Toukhsati, Samia R ;Johansson, Peter;Jaarsma, Tiny
Affiliation: Department of Cardiology, Austin Health, Heidelberg Vic 3084, Australia
Department of Medicine, University of Melbourne, Heidelberg Vic 3084, Australia Department of Cardiology, Austin Health, Heidelberg Vic 3084, Australia
Department of Health and Welfare Studies, Faculty of Health Sciences, University of Link??ping, Sweden Department of Cardiology, Link??ping University Hospital, S-58185 Link??ping, Sweden.
Issue Date: 25-Nov-2013
Publication information: European Heart Journal 2013; 35(21): 1365-72
Abstract: Cardiovascular disease (CVD) and depression are common. Patients with CVD have more depression than the general population. Persons with depression are more likely to eventually develop CVD and also have a higher mortality rate than the general population. Patients with CVD, who are also depressed, have a worse outcome than those patients who are not depressed. There is a graded relationship: the more severe the depression, the higher the subsequent risk of mortality and other cardiovascular events. It is possible that depression is only a marker for more severe CVD which so far cannot be detected using our currently available investigations. However, given the increased prevalence of depression in patients with CVD, a causal relationship with either CVD causing more depression or depression causing more CVD and a worse prognosis for CVD is probable. There are many possible pathogenetic mechanisms that have been described, which are plausible and that might well be important. However, whether or not there is a causal relationship, depression is the main driver of quality of life and requires prevention, detection, and management in its own right. Depression after an acute cardiac event is commonly an adjustment disorder than can improve spontaneously with comprehensive cardiac management. Additional management strategies for depressed cardiac patients include cardiac rehabilitation and exercise programmes, general support, cognitive behavioural therapy, antidepressant medication, combined approaches, and probably disease management programmes.
Gov't Doc #: 24282187
DOI: 10.1093/eurheartj/eht462
ORCID: 0000-0001-9554-6556
PubMed URL: 24282187
Type: Journal Article
Subjects: Cardiovascular disease
Quality of life
Antidepressive Agents.therapeutic use
Anxiety Disorders.complications
Cardiovascular Diseases.psychology.rehabilitation
Cognitive Therapy.methods
Combined Modality Therapy
Cost of Illness
Depressive Disorder.diagnosis.etiology.therapy
Early Diagnosis
Exercise Therapy.methods
Medication Adherence.psychology
Quality of Life
Randomized Controlled Trials as Topic
Risk Factors
Self Care
Social Isolation.psychology
Social Support
Appears in Collections:Journal articles

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