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|Title:||Bubble chamber clotting during continuous renal replacement therapy: vertical versus horizontal blood flow entry.||Austin Authors:||Baldwin, Ian C ;Fealy, Nigel G ;Carty, Paula ;Boyle, Martin;Kim, In Byung;Bellomo, Rinaldo||Affiliation:||Department of Intensive Care, Austin Health, Heidelberg, Victoria, Australia||Issue Date:||18-Oct-2012||Publication information:||Blood Purification 2012; 34(3-4): 213-8||Abstract:||The continuous renal replacement therapy (CRRT) bubble trap chamber is a frequent site of clotting.To assess clot formation when comparing our standard 'vertical' blood entry chamber (BEC) with a new 'horizontal' BEC.Adult ICU patients requiring CRRT were treated with the vertical BEC and then a similar subsequent cohort with the horizontal BEC in continuous veno-venous haemofiltration mode.40 chambers were assessed for each design. Circuit life was 13.9 ± 9.5 h for the vertical and 17.7 ± 15.9 h for the horizontal BEC (p = 0.33). APTT, however, was higher for the horizontal BEC (55.7 ± 34.7 vs. 37.4 ± 9.0, p < 0.002) and no difference in circuit life was found after multivariable analysis. A clotting score ≥3 was observed in 85% of all chambers. There was no difference in chamber clotting score (vertical 3.6 ± 1.03 vs. horizontal 3.8 ± 1.0, p = 0.5). In addition, no difference was found when scores were divided into two groups using a 'likelihood' to clot analysis (p = 1.0).CRRT horizontal BEC were not associated with less clotting compared to our standard vertical BEC.||Gov't Doc #:||23095781||URI:||https://ahro.austin.org.au/austinjspui/handle/1/11592||DOI:||10.1159/000342596||Journal:||Blood Purification||URL:||https://pubmed.ncbi.nlm.nih.gov/23095781||Type:||Journal Article||Subjects:||Blood Coagulation
Intensive Care Units
Renal Replacement Therapy.adverse effects.instrumentation.methods
|Appears in Collections:||Journal articles|
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