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dc.contributor.authorBaldwin, Ian Cen
dc.contributor.authorFealy, Nigel Gen
dc.contributor.authorCarty, Paulaen
dc.contributor.authorBoyle, Martinen
dc.contributor.authorKim, In Byungen
dc.contributor.authorBellomo, Rinaldoen
dc.identifier.citationBlood Purification 2012; 34(3-4): 213-8en
dc.description.abstractThe continuous renal replacement therapy (CRRT) bubble trap chamber is a frequent site of clotting.To assess clot formation when comparing our standard 'vertical' blood entry chamber (BEC) with a new 'horizontal' BEC.Adult ICU patients requiring CRRT were treated with the vertical BEC and then a similar subsequent cohort with the horizontal BEC in continuous veno-venous haemofiltration mode.40 chambers were assessed for each design. Circuit life was 13.9 ± 9.5 h for the vertical and 17.7 ± 15.9 h for the horizontal BEC (p = 0.33). APTT, however, was higher for the horizontal BEC (55.7 ± 34.7 vs. 37.4 ± 9.0, p < 0.002) and no difference in circuit life was found after multivariable analysis. A clotting score ≥3 was observed in 85% of all chambers. There was no difference in chamber clotting score (vertical 3.6 ± 1.03 vs. horizontal 3.8 ± 1.0, p = 0.5). In addition, no difference was found when scores were divided into two groups using a 'likelihood' to clot analysis (p = 1.0).CRRT horizontal BEC were not associated with less clotting compared to our standard vertical BEC.en
dc.subject.otherBlood Coagulationen
dc.subject.otherHemofiltration.adverse effects.methodsen
dc.subject.otherHospital Mortalityen
dc.subject.otherIntensive Care Unitsen
dc.subject.otherProspective Studiesen
dc.subject.otherRenal Replacement Therapy.adverse effects.instrumentation.methodsen
dc.titleBubble chamber clotting during continuous renal replacement therapy: vertical versus horizontal blood flow entry.en
dc.typeJournal Articleen
dc.identifier.journaltitleBlood Purificationen
dc.identifier.affiliationDepartment of Intensive Care, Austin Health, Heidelberg, Victoria, Australiaen
dc.type.austinJournal Articleen, Ian C
item.openairetypeJournal Article-
item.fulltextNo Fulltext-
item.grantfulltextnone- Care- Care- Care- Care- Analytics Research and Evaluation (DARE) Centre-
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