Please use this identifier to cite or link to this item: http://ahro.austin.org.au/austinjspui/handle/1/11884
Title: Internal jugular and vertebral vein volume flow in patients with clinically isolated syndrome or mild multiple sclerosis and healthy controls: results from a prospective sonographer-blinded study.
Authors: Chambers, Brian R;Chambers, Jayne;Churilov, Leonid;Cameron, Heather;Macdonell, Richard A L
Affiliation: Department of Neurology, Austin Health, Melbourne, Australia The Florey Institute of Neuroscience and Mental Health, Melbourne, Australia Department of Medicine, University of Melbourne, Victoria, Australia brc@bigpond.net.au.
The Florey Institute of Neuroscience and Mental Health, Melbourne, Australia Department of Mathematics and Statistics, University of Melbourne, Victoria, Australia.
Department of Neurology, Austin Health, Melbourne, Australia.
Department of Neurology, Austin Health, Melbourne, Australia The Florey Institute of Neuroscience and Mental Health, Melbourne, Australia Department of Medicine, University of Melbourne, Victoria, Australia.
Issue Date: 24-Sep-2013
Citation: Phlebology / Venous Forum of the Royal Society of Medicine 2013; 29(8): 528-35
Abstract: We evaluated internal jugular vein and vertebral vein volume flow using ultrasound, in patients with clinically isolated syndrome or mild multiple sclerosis and controls, to determine whether volume flow was different between the two groups.In patients and controls, internal jugular vein volume flow increased from superior to inferior segments, consistent with recruitment from collateral veins. Internal jugular vein and vertebral vein volume flow were greater on the right in supine and sitting positions. Internal jugular vein volume flow was higher in the supine posture. Vertebral vein volume flow was higher in the sitting posture. Regression analyses of cube root transformed volume flow data, adjusted for supine/sitting, right/left and internal jugular vein/vertebral vein, revealed no significant difference in volume flow in patients compared to controls.Our findings further refute the concept of venous obstruction as a causal factor in the pathogenesis of multiple sclerosis. Control volume flow data may provide useful normative reference values.
Internal ID Number: 24065289
URI: http://ahro.austin.org.au/austinjspui/handle/1/11884
DOI: 10.1177/0268355513505505
URL: http://www.ncbi.nlm.nih.gov/pubmed/24065289
Type: Journal Article
Subjects: Chronic cerebrospinal venous insufficiency
multiple sclerosis
venous ultrasound
volume flow
Adult
Angiography
Blood Flow Velocity
Humans
Jugular Veins.physiopathology.ultrasonography
Male
Middle Aged
Multiple Sclerosis.physiopathology.ultrasonography
Spine.blood supply.physiopathology.ultrasonography
Appears in Collections:Journal articles

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