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|Title:||Tumor-specific T-cell help is associated with improved survival in melanoma.|
|Authors:||Woods, Katherine;Cebon, Jonathan S|
|Affiliation:||Ludwig Institute for Cancer Research Melbourne-Austin Branch, Heidelberg, Australia.|
|Citation:||Clinical Cancer Research : An Official Journal of the American Association For Cancer Research 2013; 19(15): 4021-3|
|Abstract:||Despite success with immune checkpoint inhibitors, clinical benefit from cancer vaccines remains elusive. Combined targeting of melanoma-specific CD4(+) and CD8(+) T-lymphocyte epitopes was associated with improved survival compared with targeting either alone, or when a nonspecific helper epitope was used. We discuss the potential role of antigen-specific CD4 help.|
|Internal ID Number:||23864163|
Cancer Vaccines.immunology.therapeutic use
|Appears in Collections:||Journal articles|
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