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|Title:||Tumor-specific T-cell help is associated with improved survival in melanoma.||Austin Authors:||Woods, Katherine;Cebon, Jonathan S||Affiliation:||Ludwig Institute for Cancer Research Melbourne-Austin Branch, Heidelberg, Australia||Issue Date:||17-Jul-2013||Publication information:||Clinical Cancer Research 2013; 19(15): 4021-3||Abstract:||Despite success with immune checkpoint inhibitors, clinical benefit from cancer vaccines remains elusive. Combined targeting of melanoma-specific CD4(+) and CD8(+) T-lymphocyte epitopes was associated with improved survival compared with targeting either alone, or when a nonspecific helper epitope was used. We discuss the potential role of antigen-specific CD4 help.||Gov't Doc #:||23864163||URI:||http://ahro.austin.org.au/austinjspui/handle/1/11812||DOI:||10.1158/1078-0432.CCR-13-1349||URL:||https://pubmed.ncbi.nlm.nih.gov/23864163||Type:||Journal Article||Subjects:||Antigens, CD4.immunology
Cancer Vaccines.immunology.therapeutic use
|Appears in Collections:||Journal articles|
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