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|Title:||Spinal drop metastasis from grade I skull base chondrosarcoma.|
|Authors:||Hall, Nick D P;Fabinyi, Gavin;Gul, Shahid M;Cher, Lawrence M;Leibsch, Norbert J|
|Affiliation:||Department of Neurosurgery, Austin Hospital, PO Box 5555, Heidelberg, Victoria 3084, Australia|
|Citation:||Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia 2009; 17(1): 135-7|
|Abstract:||Chondrosarcoma of the skull base is a rare tumour with a good prognosis following surgical resection. We describe a patient with low-grade chondrosarcoma of the skull base with intradural extramedullary spinal metastases. A 31-year-old female with grade 1 chondrosarcoma involving the cavernous sinus, sphenoid wing and clivus presented at age 19. The tumour was subtotally excised at initial surgery and over the following 4 years, 3 subsequent resections were undertaken for tumour progression followed by proton beam radiotherapy to the residual tumour. The patient re-presented with cervical radiculopathy 7 years later. MRI showed multiple, intradural extramedullary spinal drop metastases. Following surgical excision of the symptomatic lesion, histological diagnosis was confirmed as a mixed hyaline/myxoid grade 1 chondrosarcoma. Patients with skull base chondrosarcoma with intradural extension should have whole spine imaging as part of long-term monitoring to exclude drop metastases, particularly after intradural surgery.|
|Internal ID Number:||19864142|
Cranial Fossa, Middle.pathology.surgery
Cranial Fossa, Posterior.pathology.surgery
Magnetic Resonance Imaging
Skull Base Neoplasms.pathology.radiotherapy.surgery
Spinal Cord Compression.etiology.pathology.physiopathology
|Appears in Collections:||Journal articles|
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