Please use this identifier to cite or link to this item: http://ahro.austin.org.au/austinjspui/handle/1/10910
Title: Spinal drop metastasis from grade I skull base chondrosarcoma.
Authors: Hall, Nick D P;Fabinyi, Gavin;Gul, Shahid M;Cher, Lawrence M;Leibsch, Norbert J
Affiliation: Department of Neurosurgery, Austin Hospital, PO Box 5555, Heidelberg, Victoria 3084, Australia. drndphall@mac.com
Issue Date: 27-Oct-2009
Citation: Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia 2009; 17(1): 135-7
Abstract: Chondrosarcoma of the skull base is a rare tumour with a good prognosis following surgical resection. We describe a patient with low-grade chondrosarcoma of the skull base with intradural extramedullary spinal metastases. A 31-year-old female with grade 1 chondrosarcoma involving the cavernous sinus, sphenoid wing and clivus presented at age 19. The tumour was subtotally excised at initial surgery and over the following 4 years, 3 subsequent resections were undertaken for tumour progression followed by proton beam radiotherapy to the residual tumour. The patient re-presented with cervical radiculopathy 7 years later. MRI showed multiple, intradural extramedullary spinal drop metastases. Following surgical excision of the symptomatic lesion, histological diagnosis was confirmed as a mixed hyaline/myxoid grade 1 chondrosarcoma. Patients with skull base chondrosarcoma with intradural extension should have whole spine imaging as part of long-term monitoring to exclude drop metastases, particularly after intradural surgery.
Internal ID Number: 19864142
URI: http://ahro.austin.org.au/austinjspui/handle/1/10910
DOI: 10.1016/j.jocn.2009.02.033
URL: http://www.ncbi.nlm.nih.gov/pubmed/19864142
Type: Journal Article
Subjects: Adult
Cavernous Sinus.pathology.surgery
Cervical Vertebrae.pathology.surgery
Chondrosarcoma.radiotherapy.secondary.surgery
Cranial Fossa, Middle.pathology.surgery
Cranial Fossa, Posterior.pathology.surgery
Female
Humans
Magnetic Resonance Imaging
Neoplasm Metastasis.pathology.therapy
Neurosurgical Procedures.methods
Paresthesia.etiology
Radiculopathy.etiology
Radiotherapy.methods
Sella Turcica.pathology.surgery
Skull Base.pathology.surgery
Skull Base Neoplasms.pathology.radiotherapy.surgery
Sphenoid Bone.pathology.surgery
Spinal Cord Compression.etiology.pathology.physiopathology
Spinal Neoplasms.secondary.surgery
Treatment Outcome
Appears in Collections:Journal articles

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