Austin Health

Title
Spinal drop metastasis from grade I skull base chondrosarcoma.
Publication Date
2009-10-27
Author(s)
Hall, Nick D P
Fabinyi, Gavin C
Gul, Shahid M
Cher, Lawrence M
Leibsch, Norbert J
Type of document
Journal Article
DOI
10.1016/j.jocn.2009.02.033
Abstract
Chondrosarcoma of the skull base is a rare tumour with a good prognosis following surgical resection. We describe a patient with low-grade chondrosarcoma of the skull base with intradural extramedullary spinal metastases. A 31-year-old female with grade 1 chondrosarcoma involving the cavernous sinus, sphenoid wing and clivus presented at age 19. The tumour was subtotally excised at initial surgery and over the following 4 years, 3 subsequent resections were undertaken for tumour progression followed by proton beam radiotherapy to the residual tumour. The patient re-presented with cervical radiculopathy 7 years later. MRI showed multiple, intradural extramedullary spinal drop metastases. Following surgical excision of the symptomatic lesion, histological diagnosis was confirmed as a mixed hyaline/myxoid grade 1 chondrosarcoma. Patients with skull base chondrosarcoma with intradural extension should have whole spine imaging as part of long-term monitoring to exclude drop metastases, particularly after intradural surgery.
Link
Citation
Journal of Clinical Neuroscience 2009; 17(1): 135-7
Jornal Title
Journal of Clinical Neuroscience

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