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Title: New insights into the molecular biology of the glomerular filtration barrier and associated disease.
Austin Authors: Levidiotis, Vicki;Power, David Anthony
Affiliation: Austin Research Institute, Department of Nephrology, Austin Health, Heidelberg, Victoria, Australia
Issue Date: 1-Apr-2005
Publication information: Nephrology; 10(2): 157-66
Abstract: The glomerular filtration barrier of the kidney can no longer be considered as an inert and adynamic structure, viewed by electron microscopy. Molecular biology, medical genetics and protein chemistry have enabled us to further understand the complex structure and function of this highly specialized barrier of the kidney. Minor aberrations of physiology can lead to fatal disease. Recent advances in the understanding of the physiology of endothelial cells, glomerular epithelial cells and the glomerular basement membrane and its components, and how these relate to disease, will be considered systematically.
Gov't Doc #: 15877676
DOI: 10.1111/j.1440-1797.2005.00385.x
Journal: Nephrology
Type: Journal Article
Subjects: Animals
Basement Membrane.pathology.physiology
Collagen Type IV.genetics
Kidney Diseases.genetics.pathology.physiopathology
Kidney Glomerulus.pathology.physiology
Appears in Collections:Journal articles

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