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Title: Chronic persistent cough: use of ipratropium bromide in undiagnosed cases following upper respiratory tract infection.
Austin Authors: Holmes, Peter W;Barter, C E;Pierce, Robert J
Affiliation: Department of Respiratory Medicine, Heidelberg Repatriation Hospital, Melbourne, Victoria, Australia
Issue Date: 1-Sep-1992
Publication information: Respiratory Medicine; 86(5): 425-9
Abstract: The clinical effects of inhaled ipratropium bromide were studied in 14 non-smoking patients with persistent post-viral infective cough employing a controlled double-blind, cross-over trial. Patients were selected if they demonstrated no apparent underlying cause for their persistent cough after appropriate radiological and respiratory function tests including methacholine reactivity and bronchoscopic examination. Inhaled ipratropium bromide (320 micrograms day-1) produced significantly less day and night time cough (P < 0.05) with overall clinical improvement in 12 cases, five of whom had total resolution of their cough. We conclude that ipratropium bromide is an effective treatment in non-smoking adults with protracted cough following clinical upper respiratory tract infection.
Gov't Doc #: 1462022
Type: Journal Article
Subjects: Administration, Inhalation
Chronic Disease
Cough.drug therapy.microbiology.physiopathology
Double-Blind Method
Forced Expiratory Volume.drug effects
Ipratropium.administration & dosage
Middle Aged
Respiratory Tract Infections.complications
Vital Capacity.drug effects
Appears in Collections:Journal articles

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