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Title: Brief comprehensive quality of life assessment after stroke: the assessment of quality of life instrument in the north East melbourne stroke incidence study (NEMESIS).
Austin Authors: Sturm, Jonathan W;Osborne, Richard H;Dewey, Helen M;Donnan, Geoffrey A ;Macdonell, Richard A L ;Thrift, Amanda G
Affiliation: National Stroke Research Institute, Department of Neurology, Austin, Australia
Issue Date: 1-Dec-2002
Publication information: Stroke; A Journal of Cerebral Circulation; 33(12): 2888-94
Abstract: Generic utility health-related quality of life instruments are useful in assessing stroke outcome because they facilitate a broader description of the disease and outcomes, allow comparisons between diseases, and can be used in cost-benefit analysis. The aim of this study was to validate the Assessment of Quality of Life (AQoL) instrument in a stroke population.Ninety-three patients recruited from the community-based North East Melbourne Stroke Incidence Study between July 13, 1996, and April 30, 1997, were interviewed 3 months after stroke. Validity of the AQoL was assessed by examining associations between the AQoL and comparator instruments: the Medical Outcomes Short-Form Health Survey (SF-36); London Handicap Scale; Barthel Index; National Institutes of Health Stroke Scale; and Irritability, Depression, Anxiety scale. Sensitivity of the AQoL was assessed by comparing AQoL scores from groups of patients categorized by severity of impairment and disability and with total anterior circulation syndrome (TACS) versus non-TACS. Predictive validity was assessed by examining the association between 3-month AQoL scores and outcomes of death or institutionalization 12 months after stroke.Overall AQoL utility scores and individual dimension scores were most highly correlated with relevant scales on the comparator instruments. AQoL scores clearly differentiated between patients in categories of severity of impairment and disability and between patients with TACS and non-TACS. AQoL scores at 3 months after stroke predicted death and institutionalization at 12 months.The AQoL demonstrated strong psychometric properties and appears to be a valid and sensitive measure of health-related QoL after stroke.
Gov't Doc #: 12468787
Type: Journal Article
Subjects: Adult
Aged, 80 and over
Disability Evaluation
Follow-Up Studies
Interview, Psychological.standards
Middle Aged
Predictive Value of Tests
Psychological Tests.standards
Quality of Life.psychology
Recovery of Function
Sensitivity and Specificity
Severity of Illness Index
Sickness Impact Profile
Treatment Outcome
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