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https://ahro.austin.org.au/austinjspui/handle/1/9414| Title: | Seizure-associated hippocampal volume loss: a longitudinal magnetic resonance study of temporal lobe epilepsy. | Austin Authors: | Briellmann, Regula S;Berkovic, Samuel F ;Syngeniotis, Ari;King, Mark A;Jackson, Graeme D | Affiliation: | Brain Research Institute, Department of Neurology, Austin and Repatriation Medical Centre, University of Melbourne, Australia | Issue Date: | 1-May-2002 | Publication information: | Annals of Neurology; 51(5): 641-4 | Abstract: | This longitudinal quantitative magnetic resonance imaging study of 24 patients with mild temporal lobe epilepsy shows an ipsilateral hippocampal volume decrease of 9% (range, -30 to +0.5%; p = 0.002, paired t test) over a period of 3.5 +/- 0.7 years. The hippocampal volume loss was correlated to the number of generalized seizures between the scans (p = 0.0007, r = 0.6), suggesting seizure-associated hippocampal damage. | Gov't Doc #: | 12112114 | URI: | https://ahro.austin.org.au/austinjspui/handle/1/9414 | DOI: | 10.1002/ana.10171 | Journal: | Annals of Neurology | URL: | https://pubmed.ncbi.nlm.nih.gov/12112114 | Type: | Journal Article | Subjects: | Adolescent Adult Atrophy Epilepsy, Temporal Lobe.pathology Female Hippocampus.pathology Humans Longitudinal Studies Magnetic Resonance Imaging.statistics & numerical data Male Middle Aged Prospective Studies Regression Analysis Seizures.pathology |
| Appears in Collections: | Journal articles |
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