Please use this identifier to cite or link to this item: https://ahro.austin.org.au/austinjspui/handle/1/9414
Title: Seizure-associated hippocampal volume loss: a longitudinal magnetic resonance study of temporal lobe epilepsy.
Austin Authors: Briellmann, Regula S;Berkovic, Samuel F ;Syngeniotis, Ari;King, Mark A;Jackson, Graeme D 
Affiliation: Brain Research Institute, Department of Neurology, Austin and Repatriation Medical Centre, University of Melbourne, Australia
Issue Date: 1-May-2002
Publication information: Annals of Neurology; 51(5): 641-4
Abstract: This longitudinal quantitative magnetic resonance imaging study of 24 patients with mild temporal lobe epilepsy shows an ipsilateral hippocampal volume decrease of 9% (range, -30 to +0.5%; p = 0.002, paired t test) over a period of 3.5 +/- 0.7 years. The hippocampal volume loss was correlated to the number of generalized seizures between the scans (p = 0.0007, r = 0.6), suggesting seizure-associated hippocampal damage.
Gov't Doc #: 12112114
URI: https://ahro.austin.org.au/austinjspui/handle/1/9414
DOI: 10.1002/ana.10171
Journal: Annals of Neurology
URL: https://pubmed.ncbi.nlm.nih.gov/12112114
Type: Journal Article
Subjects: Adolescent
Adult
Atrophy
Epilepsy, Temporal Lobe.pathology
Female
Hippocampus.pathology
Humans
Longitudinal Studies
Magnetic Resonance Imaging.statistics & numerical data
Male
Middle Aged
Prospective Studies
Regression Analysis
Seizures.pathology
Appears in Collections:Journal articles

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