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Title
Seizure-associated hippocampal volume loss: a longitudinal magnetic resonance study of temporal lobe epilepsy.
Publication Date
2002-05-01
Author(s)
Briellmann, Regula S
Berkovic, Samuel F
Syngeniotis, Ari
King, Mark A
Jackson, Graeme D
Type of document
Journal Article
DOI
10.1002/ana.10171
Abstract
This longitudinal quantitative magnetic resonance imaging study of 24 patients with mild temporal lobe epilepsy shows an ipsilateral hippocampal volume decrease of 9% (range, -30 to +0.5%; p = 0.002, paired t test) over a period of 3.5 +/- 0.7 years. The hippocampal volume loss was correlated to the number of generalized seizures between the scans (p = 0.0007, r = 0.6), suggesting seizure-associated hippocampal damage.
Link
Citation
Annals of Neurology; 51(5): 641-4
Jornal Title
Annals of Neurology

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