Hippocampal sclerosis following brief generalized seizures in adulthood.

2001-07-24

Briellmann, Regula S

Newton, Mark R

Wellard, R M

Jackson, Graeme D

Journal Article

This report describes a patient who had a first generalized tonic clonic seizure (GTCS) at the age of 18 years. The initial MRI scan was normal on visual and quantitative examination. After a further six GTCS, a second MRI scan showed reduced hippocampal volume and increased hippocampal T2 signal, which was confirmed in a third scan. Therefore, hippocampal sclerosis may be acquired in adulthood after brief GTCS.

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Neurology; 57(2): 315-7

Neurology