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Title: No evidence of hypoxic tissue on 18F-fluoromisonidazole PET after intracerebral hemorrhage.
Austin Authors: Hirano, T;Read, Stephen J;Abbott, David F ;Sachinidis, John I;Tochon-Danguy, Henri;Egan, Gary F;Bladin, Christopher;Scott, Andrew M ;McKay, W J;Donnan, Geoffrey A 
Affiliation: National Stroke Research Institute, Austin and Repatriation Medical Center, West Heidelberg, Victoria, Australia
Issue Date: 10-Dec-1999
Publication information: Neurology; 53(9): 2179-82
Abstract: We studied six patients after intracerebral hemorrhage (ICH) and eight controls using positron emission tomography (PET) with to determine whether a zone of tissue hypoxia, possibly representing "penumbral" tissue, exists surrounding an intracerebral hemorrhage. None of the stroke patients, studied 24 to 43 hours after symptom onset, nor any of the controls exhibited areas of tissue hypoxia on 18F-fluoromisonidazole PET images. These findings may have implications for the treatment of intracerebral hemorrhage with neuroprotective strategies.
Gov't Doc #: 10599802
Journal: Neurology
Type: Journal Article
Subjects: Aged
Aged, 80 and over
Cerebral Hemorrhage.radionuclide imaging
Fluorine Radioisotopes.diagnostic use
Hypoxia, Brain.radionuclide imaging
Misonidazole.analogs & derivatives.diagnostic use
Radiation-Sensitizing Agents.diagnostic use
Sensitivity and Specificity
Stroke.radionuclide imaging
Tomography, Emission-Computed
Appears in Collections:Journal articles

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