Please use this identifier to cite or link to this item: https://ahro.austin.org.au/austinjspui/handle/1/35501
Title: Evaluating diagnostic tools, outcome measures and antibiotic approach in diabetic foot osteomyelitis: a scoping review and narrative synthesis.
Austin Authors: Motaganahalli, Satwik;Reynolds, Gemma;Haikerwal, Suresh;Richards, Toby;Peel, Trisha N;Trubiano, Jason 
Affiliation: Department of Infectious Diseases, The Peter Doherty Institute for Infection and Immunity, The University of Melbourne, Melbourne, Victoria, Australia.
Infectious Diseases
Division of Surgery, University College London, London, UK.;Faculty of Health and Medical Sciences, University of Western Australia, Perth, Western Australia, Australia.
Department of Infectious Diseases, The Alfred Hospital and Central Clinical School, Monash University, Melbourne, Victoria, Australia.
Issue Date: 16-Sep-2024
Date: 2024
Publication information: Expert Review of Anti-infective Therapy 2024-09-16
Abstract: Diabetic foot osteomyelitis (DFO) is a significant complication of diabetic foot disease; however, diagnosis remains challenging and treatment success is difficult to ascertain. Literature in this space that has utilized varying diagnostic criteria and ideal outcome measures for success is unclear. This scoping review assesses methods of diagnosis of DFO and definitions of treatment outcomes in the literature assessing antibiotic therapy for treatment of DFO. There is a lack of consensus in the design of diabetic foot trials, resulting in difficulty for clinicians to assess and manage serious conditions such as DFO. The cure for DFO is challenging to ascertain and treatment failure may be a better approach to assess outcomes in research assessing the efficacy of antibiotic therapy. In the absence of gold-standard diagnostic tools, practical approaches to outcome assessment may allow for greater clinical applicability of available data.
URI: https://ahro.austin.org.au/austinjspui/handle/1/35501
DOI: 10.1080/14787210.2024.2403145
ORCID: 0000-0002-6739-0424
0000-0002-9561-3592
0000-0001-9872-4653
0000-0003-2370-2438
0000-0002-5111-6367
Journal: Expert Review of Anti-infective Therapy
Start page: 1
End page: 9
PubMed URL: 39254257
ISSN: 1744-8336
Type: Journal Article
Subjects: Diabetic foot infection
antibiotic
diabetes
diagnostics
foot ulcer
osteomyelitis
Appears in Collections:Journal articles

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