Please use this identifier to cite or link to this item: https://ahro.austin.org.au/austinjspui/handle/1/34880
Title: Insulinoma: Metastatic Recurrence 38 Years Following Initial Diagnosis in Pregnancy.
Austin Authors: Preston, Christopher A;Sachithanandan, Nirupa;Sim, Ie-Wen;van Heerden, Jon;Farrell, Stephen G 
Affiliation: Department of Endocrinology & Diabetes, St Vincent's Hospital Melbourne, Fitzroy, Victoria 3065, Australia.;Department of Endocrinology & Diabetes, Western Health, Melbourne, Victoria 3021, Australia.
Department of Medicine, The University of Melbourne, Fitzroy, Victoria 3065, Australia.
Department of Endocrinology & Diabetes, Western Health, Melbourne, Victoria 3021, Australia.;Department of Medicine, The University of Melbourne, Fitzroy, Victoria 3065, Australia.;Department of Endocrinology & Diabetes, Monash Health and Eastern Health, Melbourne, Victoria 3168, Australia.;Department of Medicine, Monash University, Clayton, Victoria 3168, Australia.
Department of Surgery, Mayo Medical School, Rochester, MN 55905, USA.;Department of Surgery, Mayo Medical School, Mayo Clinic, Rochester, MN 55905, USA.;Department of Surgery, Medical University of South Carolina, Charleston 29425, USA.
Department of Surgery, St Vincent's Hospital Melbourne, Fitzroy, Victoria 3065, Australia
Surgery (University of Melbourne)
Issue Date: Feb-2024
Date: 2024
Publication information: JCEM Case Reports 2024-02; 2(2)
Abstract: A case of recurrent insulinoma spanning 4 decades is described. Following a delayed diagnosis, hyperinsulinemic hypoglycemia was confirmed in a 24-year-old woman during early pregnancy. Initial surgery, culminating in subtotal pancreatectomy, was noncurative. A 1-cm insulinoma was subsequently resected from the head of the pancreas postpartum, with postoperative resolution of hypoglycemia. However, 32 years later, the patient experienced a recurrence of hypoglycemic symptoms. Eventually, a subcentimeter extrapancreatic lesion was identified anterior to the pancreatic head on gallium-68 DOTA-Exendin-4 positron emission tomography/computed tomography. In 2022, a third operation was performed, with excision of a 4 × 3 mm tumor adjacent to the pancreatic head, and histology confirming insulinoma. She was again cured of symptoms.
URI: https://ahro.austin.org.au/austinjspui/handle/1/34880
DOI: 10.1210/jcemcr/luad168
ORCID: 0009-0004-2592-942X
0000-0002-5074-0846
Journal: JCEM Case Reports
Start page: luad168
PubMed URL: 38196815
ISSN: 2755-1520
Type: Journal Article
Subjects: Ga-68 GLP-1 PET
insulinoma
pregnancy
recurrence
Appears in Collections:Journal articles

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