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Title: Early intervention treatment in the first 2 weeks following concussion in adults: A systematic review of randomised controlled trials.
Austin Authors: Moore, Sonya;Musgrave, Chris;Sandler, Jonathan;Bradley, Ben;Jones, Jennifer R A 
Affiliation: Physiotherapy Department, The University of Melbourne, Parkville, Victoria, Australia.
Institute for Breathing and Sleep
Issue Date: Jan-2024
Date: 2023
Publication information: Physical Therapy in Sport : Official Journal of the Association of Chartered Physiotherapists in Sports Medicine 2024-01; 65
Abstract: International guidelines support a repertoire of therapeutic interventions that may assist recovery following concussion. We aimed to systematically review the efficacy of early pharmacological and non-pharmacological interventions initiated within two weeks of injury on symptoms and functional recovery of adults with concussion. We conducted a Systematic Review (SR) of Randomised Controlled Trials (RCTs) without meta-analysis utilising the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. A comprehensive search was performed of four databases. Study inclusion criteria were adult participants diagnosed with concussion and commencing active intervention within 14 days of injury. Of 7531 studies identified, 11 were included in the final review. Six studies were rated as high-risk of bias, three with some concerns and two as low-risk of bias. We found no evidence to support specific pharmacotherapeutic management to hasten the natural recovery time-course. Two studies reported significant improvement in selected concussion symptoms following manual therapy (at 48-72┬áhours post-treatment) or telephone counselling interventions (at 6 months post-injury). No high quality RCTs demonstrate superior effects of early therapeutic interventions on concussion recovery in the first 2 weeks. We advocate future research to examine impacts of health-clinician contact points aligned with symptom-specific interventions.
DOI: 10.1016/j.ptsp.2023.11.005
Journal: Physical Therapy in Sport : Official Journal of the Association of Chartered Physiotherapists in Sports Medicine
Start page: 59
End page: 73
PubMed URL: 38065015
ISSN: 1873-1600
Type: Journal Article
Subjects: Head injury
Practice guideline
Appears in Collections:Journal articles

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