Please use this identifier to cite or link to this item: https://ahro.austin.org.au/austinjspui/handle/1/33527
Title: Smaller Return Cannula in Venoarterial Extracorporeal Membrane Oxygenation Does Not Increase Hemolysis: A Single-Center, Cohort Study.
Austin Authors: Joyce, Patrick R;Hodgson, Carol L;Bellomo, Rinaldo ;Gregory, Shaun D;Raman, Jaishankar;Stephens, Andrew F;Taylor, Kieran;Paul, Eldho;Wickramarachchi, Avishka;Burrell, Aidan
Affiliation: From the Department of Intensive Care, The Alfred Hospital, Melbourne, Victoria, Australia.
The George Institute for Global Health, Sydney, New South Wales, Australia.
ANZ Intensive Care Research Centre (ANZIC-RC), Monash University, Melbourne, Victoria, Australia.;Department of Critical Care, University of Melbourne, Melbourne, Victoria, Australia.;Department of Intensive Care, Austin Hospital, Melbourne, Victoria, Australia.;Data Analytics Research and Evaluation Centre, Austin Hospital, Melbourne, Victoria, Australia.;Department of Intensive Care, Royal Melbourne Hospital, Melbourne, Victoria, Australia.
Cardio-Respiratory Engineering and Technology Laboratory (CREATElab), Department of Mechanical and Aerospace Engineering, Monash University, Clayton, Victoria, Australia
Department of Critical Care, University of Melbourne, Melbourne, Victoria, Australia.
St Vincent's Hospital, Melbourne, Victoria, Australia.
Department of Critical Care, University of Melbourne, Melbourne, Victoria, Australia.
Department of Epidemiology and Preventive Medicine, Monash University, Melbourne, Victoria, Australia.
Cardio-Respiratory Engineering and Technology Laboratory (CREATElab), Department of Mechanical and Aerospace Engineering, Monash University, Clayton, Victoria, Australia; and.
Department of Epidemiology and Preventive Medicine, Monash University, Melbourne, Victoria, Australia.
Intensive Care
Issue Date: 1-Nov-2023
Date: 2023
Publication information: ASAIO Journal (American Society for Artificial Internal Organs : 1992) 2023-11-01; 69(11)
Abstract: The aim of this study was to explore the association between arterial return cannula diameter and hemolysis during peripheral VA ECMO. We identified 158 adult patients who received peripheral VA ECMO at our institution from the national ECMO database (EXCEL) between January 2019 and July 2021. We classified patients into a small cannula group (15 Fr diameter, n = 45) and a large cannula group (≥17 Fr diameter, n = 113), comparing incidences of clinical hemolysis and plasma free hemoglobin (pfHb). Moderate hemolysis is defined as having pfHb 0.05-0.10 g/L and severe hemolysis as having pfHb >0.10 g/L sustained for at least two consecutive readings or leading to a circuit change. There were no significant differences in rates of moderate hemolysis between small and large cannula groups (1 vs. 6; p = 0.39) and severe hemolysis (0 vs. 3; p = 0.27), nor was the pfHb level significantly different at 4 hours (0.086 ± 0.096 vs. 0.112 ± 0.145 g/L; p = 0.58) and at 24 hours (0.042 ± 0.033 vs. 0.051 ± 0.069 g/L; p = 0.99). There were no increased rates of hemolysis when comparing small versus large arterial return cannula diameter in peripheral VA ECMO.
URI: https://ahro.austin.org.au/austinjspui/handle/1/33527
DOI: 10.1097/MAT.0000000000002027
ORCID: 
Journal: ASAIO Journal (American Society for Artificial Internal Organs : 1992)
PubMed URL: 37549666
ISSN: 1538-943X
Type: Journal Article
Appears in Collections:Journal articles

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