Please use this identifier to cite or link to this item: https://ahro.austin.org.au/austinjspui/handle/1/33471
Title: Challenges and priorities for researching the gut microbiota in individuals living with anorexia nervosa.
Austin Authors: West, Madeline L;Hart, Susan;Loughman, Amy;Jacka, Felice N;Staudacher, Heidi M;Abbaspour, Afrouz;Phillipou, Andrea ;Ruusunen, Anu;Rocks, Tetyana
Affiliation: Deakin University, IMPACT - The Institute for Mental and Physical Health and Clinical Translation, Food & Mood Centre, School of Medicine, Barwon Health, Geelong, Australia.
Eating and Nutrition Research Group, School of Medicine, Western Sydney University, Cambelltown, Australia.;Nutrition Services, St Vincent's Health Network, Darlinghurst, Australia.;Translational Health Research Institute, Eating Disorders and Body Image, School of Medicine, Western Sydney University, Penrith, New South Wales, Australia.
Deakin University, IMPACT - The Institute for Mental and Physical Health and Clinical Translation, Food & Mood Centre, School of Medicine, Barwon Health, Geelong, Australia.;Centre for Adolescent Health, Murdoch Children's Research Institute, Parkville, Victoria, Australia.;Black Dog Institute, Randwick, New South Wales, Australia.;James Cook University, Townsville, Queensland, Australia.
Department of Medical Epidemiology and Biostatistics, Karolinska Institutetet, Solna, Stockholm, Sweden.
Orygen, Melbourne, Victoria, Australia.;Centre for Youth Mental Health, The University of Melbourne, Melbourne, Victoria, Australia.;Department of Psychological Sciences, Swinburne University of Technology, Melbourne, Victoria, Australia.;Department of Mental Health, St Vincent's Hospital, Melbourne, Victoria, Australia.;Department of Mental Health, Austin Health, Melbourne, Victoria, Australia.
Institute of Public Health and Clinical Nutrition, University of Eastern Finland, Kuopio, Finland.;Department of Psychiatry, Kuopio University Hospital, Kuopio, Finland.
Deakin University, IMPACT - The Institute for Mental and Physical Health and Clinical Translation, Food & Mood Centre, School of Medicine, Barwon Health, Geelong, Australia.;Translational Health Research Institute, Eating Disorders and Body Image, School of Medicine, Western Sydney University, Penrith, New South Wales, Australia.
Mental Health
Issue Date: Nov-2023
Date: 2023
Publication information: The International Journal of Eating Disorders 2023-11; 56(11)
Abstract: The gut microbiota is implicated in several symptoms and biological pathways relevant to anorexia nervosa (AN). Investigations into the role of the gut microbiota in AN are growing, with a specific interest in the changes that occur in response to treatment. Findings suggest that microbial species may be associated with some of the symptoms common in AN, such as depression and gastrointestinal disturbances (GID). Therefore, researchers believe the gut microbiota may have therapeutic relevance. Whilst research in this field is rapidly expanding, the unique considerations relevant to conducting gut microbiota research in individuals with AN must be addressed. We provide an overview of the published literature investigating the relationship between the gut microbiota and symptoms and behaviors present in AN, discuss important challenges in gut microbiota research, and offer recommendations for addressing these. We conclude by summarizing research design priorities for the field to move forward. Several ways exist to reduce participant burden and accommodate challenges when researching the gut microbiota in individuals with AN. Recommendations from this article are foreseen to encourage scientific rigor and thoughtful protocol planning for microbiota research in AN, including ways to reduce participant burden. Employing such methods will contribute to a better understanding of the role of the gut microbiota in AN pathophysiology and treatment. The field of gut microbiota research is rapidly expanding, including the role of the gut microbiota in anorexia nervosa. Thoughtful planning of future research will ensure appropriate data collection for meaningful interpretation while providing a positive experience for the participant. We present current challenges, recommendations for research design and priorities to facilitate the advancement of research in this field.
URI: https://ahro.austin.org.au/austinjspui/handle/1/33471
DOI: 10.1002/eat.24033
ORCID: 0000-0002-6590-0486
0000-0002-0257-1443
0000-0002-9825-0328
0000-0001-6704-2131
0000-0002-1337-0102
0000-0003-1009-6619
0000-0002-1169-7478
Journal: The International Journal of Eating Disorders
PubMed URL: 37548294
ISSN: 1098-108X
Type: Journal Article
Subjects: anorexia nervosa
eating disorder
gut microbiome
gut microbiota
Appears in Collections:Journal articles

Files in This Item:
File Description SizeFormat 
Intl J Eating Disorders - 2023 - West.pdf1.53 MBAdobe PDFThumbnail
View/Open
Show full item record

Page view(s)

10
checked on Apr 19, 2024

Download(s)

2
checked on Apr 19, 2024

Google ScholarTM

Check


Items in AHRO are protected by copyright, with all rights reserved, unless otherwise indicated.