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Title: Outcomes and complications of nonagenarians undergoing cardiac surgery: a scoping review protocol.
Austin Authors: Ludski, Jarryd;Carp, Bradly;Makar, Tim;Yii, Michael;Lee, Dong-Kyu;Weinberg, Laurence 
Affiliation: Anaesthesia
Department of Cardiac Surgery, Epworth Eastern Hospital, Box Hill, Victoria, Australia.
Department of Anesthesiology and Pain Medicine, Dongguk University Ilsan Hospital, Goyang, Korea (the Republic of).
Department of Critical Care, University of Melbourne, Parkville, Victoria, Australia.
Issue Date: 18-Jul-2023
Date: 2023
Publication information: BMJ Open 2023-07-18; 13(7)
Abstract: Continually rising life expectancy and a shift towards an ageing population are resulting in an increasing population of nonagenarians. By 2030, the global population of nonagenarians is expected to exceed 30 million. The incidence of symptomatic cardiac disease is reported to occur in 25% of those aged over 75 years. Therefore, the number of nonagenarians undergoing cardiac surgery is also expected to increase. A linear relationship between advanced age and surgical risk has previously been demonstrated; however, it is not yet known whether this knowledge extends to the perioperative course and mortality of nonagenarians undergoing cardiac surgery. This scoping review aims to review the literature, assess whether a deficiency exists in the published literature and potentially identify knowledge gaps to guide future efforts to improve the understanding of nonagenarians undergoing cardiac surgery. Following the relevant aspects of the Preferred Reporting Items for Systematic Review and Meta-Analysis Extension for Scoping Review guidelines, electronic databases of MEDLINE, EMBASE and the Cochrane Library will be systematically searched, with additional reference tracking of eligible studies. Studies reporting the outcomes of nonagenarians undergoing open cardiac surgery or minimally invasive cardiac surgery requiring cardiopulmonary bypass will be included. Screening and data extraction will be performed by two reviewers independently. The data will be analysed and summarised descriptively with a narrative approach. Qualitative data that capture quality-of-life outcomes will be subjected to thematic analysis where feasible. Additionally, reporting results will highlight similarities and differences in nonagenarian selection for surgery. Ethics approval was not required. The findings will be disseminated through professional networks, conference presentations and publications in scientific journals.
DOI: 10.1136/bmjopen-2023-072293
ORCID: 0000-0001-7403-7680
Journal: BMJ Open
Start page: e072293
PubMed URL: 37463807
ISSN: 2044-6055
Type: Journal Article
Subjects: Adult anaesthesia
Cardiac surgery
Cardiothoracic surgery
Cardiac Surgical Procedures/adverse effects
Heart Diseases/epidemiology
Heart Diseases/surgery
Appears in Collections:Journal articles

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