Please use this identifier to cite or link to this item: https://ahro.austin.org.au/austinjspui/handle/1/33252
Title: Patterns of care for people with small cell lung cancer in Victoria, 2011-19: a retrospective, population-based registry data study.
Austin Authors: Huang, Joanna;Faisal, Wasek;Brand, Margaret;Smith, Shantelle;Alexander, Marliese;Briggs, Lisa;Conron, Matthew;Duffy, Mary;John, Thomas ;Langton, David;Lesage, Jacqueline;MacManus, Michael;Mitchell, Paul L R ;Olesen, Inger;Parente, Phillip;Philip, Jennifer;Samuel, Evangeline;Torres, Javier;Underhill, Craig R;Zalcberg, John R;Harden, Susan;Stirling, Rob
Affiliation: Alfred Health, Melbourne, VIC.
Grampians Health, Ballarat, VIC.
Peter MacCallum Cancer Institute, Melbourne, VIC.;The University of Melbourne, Melbourne, VIC.
Monash University, Melbourne, VIC.
The University of Melbourne, Melbourne, VIC.;St Vincent's Hospital Melbourne, Melbourne, VIC.
Peter MacCallum Cancer Institute, Melbourne, VIC.
Peninsula Health, Melbourne, VIC.
Olivia Newton-John Cancer Wellness and Research Centre
Andrew Love Cancer Centre, Barwon Health, Geelong, VIC.
Eastern Health Clinical School, Monash University, Melbourne, VIC.;Eastern Health, Melbourne, VIC.
The University of Melbourne, Melbourne, VIC.
Latrobe Regional Hospital, Traralgon, VIC.
Goulburn Valley Health, Shepparton, VIC.
Albury Wodonga Health, Wodonga, NSW.;The University of New South Wales, Sydney, NSW.
Monash University Central Clinical School, Melbourne, VIC.
Issue Date: 7-Aug-2023
Date: 2023
Publication information: The Medical Journal of Australia 2023-08-07; 219(3)
Abstract: To report stage-specific patterns of treatment and the influence of management and treatment type on survival rates for people newly diagnosed with small cell lung cancer (SCLC). Cross-sectional patterns of care study; analysis of data prospectively collected for the Victorian Lung Cancer Registry (VLCR). All people diagnosed with SCLC in Victoria during 1 April 2011 - 18 December 2019. Stage-specific management and treatment of people with SCLC; median survival time. During 2011-19, 1006 people were diagnosed with SCLC (10.5% of all lung cancer diagnoses in Victoria); their median age was 69 years (interquartile range [IQR], 62-77 years), 429 were women (43%), and 921 were current or former smokers (92%). Clinical stage was defined for 896 people (89%; TNM stages I-III, 268 [30%]; TNM stage IV, 628 [70%]) and ECOG performance status at diagnosis for 663 (66%; 0 or 1, 489 [49%]; 2-4, 174 [17%]). The cases of 552 patients had been discussed at multidisciplinary meetings (55%), 377 people had received supportive care screening (37%), and 388 had been referred for palliative care (39%). Active treatment was received by 891 people (89%): chemotherapy, 843 (84%); radiotherapy, 460 (46%); chemotherapy and radiotherapy, 419 (42%); surgery, 23 (2%). Treatment had commenced within fourteen days of diagnosis for 632 of 875 patients (72%). Overall median survival time from diagnosis was 8.9 months (IQR, 4.2-16 months; stage I-III: 16.3 [IQR, 9.3-30] months; stage IV: 7.2 [IQR, 3.3-12] months). Multidisciplinary meeting presentation (hazard ratio [HR], 0.66; 95% CI, 0.58-0.77), multimodality treatment (HR, 0.42; 95% CI, 0.36-0.49), and chemotherapy within fourteen days of diagnosis (HR, 0.68; 95% CI, 0.48-0.94) were each associated with lower mortality during follow-up. Rates of supportive care screening, multidisciplinary meeting evaluation, and palliative care referral for people with SCLC could be improved. A national registry of SCLC-specific management and outcomes data could improve the quality and safety of care.
URI: https://ahro.austin.org.au/austinjspui/handle/1/33252
DOI: 10.5694/mja2.52017
ORCID: 0000-0001-7317-4958
0000-0001-9335-2678
0000-0001-9877-5450
Journal: The Medical Journal of Australia
PubMed URL: 37365486
ISSN: 1326-5377
Type: Journal Article
Subjects: Cancer
Chemotherapy
Guidelines as topic
Lung diseases
Neoplasms, epidemiology
Quality assurance, health care
Quality of health care
Radiotherapy
Appears in Collections:Journal articles

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